Identification of genotoxic components of the heavy ends of energy-related materials
- Brigham Young Univ., Provo, UT (USA). Dept. of Chemistry
- University of South Florida, Tampa, FL (USA). Dept. of Chemistry
The objective of this work was to develop capillary supercritical fluid chromatographic methods for the analysis of the high-molecular-weight components in high boiling, heavy and materials that are responsible for genotoxic activity. Since these compounds were largely unknown, 62 standard reference compounds were synthesized for comparison with actual high boiling coal-derived products. These compounds were comprised of two- and three-ring aromatic moieties coupled together with carbon, oxygen, sulfur, and nitrogen bridging groups. Mass spectral evidence indicated that a number of these compound types could be present in various coal products at a concentration level of 0.01--0.2 percent, although none of them could be positively identified because of the complexities of the fractions. A number of capillary supercritical fluid chromatographic instrumental developments were made as a result of this work. These include a supercritical fluid fractionation system for group-type separation of complex samples and a direct coupled supercritical fluid chromatograph/double focusing mass spectrometer system. Finally, a number of supercritical fluid chromatographic mobile phase combinations were evaluated for the analysis of large polycyclic aromatic compounds. 34 refs., 23 figs., 2 tabs.
- Research Organization:
- Brigham Young Univ., Provo, UT (USA). Dept. of Chemistry
- Sponsoring Organization:
- DOE/ER
- DOE Contract Number:
- FG02-86ER60445
- OSTI ID:
- 7007668
- Report Number(s):
- DOE/ER/60445-4; ON: DE90008373
- Country of Publication:
- United States
- Language:
- English
Similar Records
Chemical characterization of thermal maturity in coals using high-resolution chromatographic methods. Annual report, May 1988-April 1989
Supercritical fluid chromatography of polar organic compounds in combustion particulates. Final report. Report for 28 September 1984-31 August 1987
Related Subjects
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
54 ENVIRONMENTAL SCIENCES
AROMATICS
SUPERCRITICAL FLUID CHROMATOGRAPHY
POLYCYCLIC AROMATIC HYDROCARBONS
FRACTIONATION
MASS SPECTROSCOPY
MOLECULAR WEIGHT
PHYSICAL PROPERTIES
PROGRESS REPORT
SOLUBILITY
SYNTHESIS
CHROMATOGRAPHY
DOCUMENT TYPES
HYDROCARBONS
ORGANIC COMPOUNDS
SEPARATION PROCESSES
SPECTROSCOPY
400102* - Chemical & Spectral Procedures
540120 - Environment
Atmospheric- Chemicals Monitoring & Transport- (1990-)