Manganese(II) induces cell division and increases in superoxide dismutase and catalase activities in an aging deinococcal culture
- National Tsing Hua Univ., Taiwan (China)
Addition of Mn(II) at 2.5 microM or higher to stationary-phase cultures of Deinococcus radiodurans IR was found to trigger at least three rounds of cell division. This Mn(II)-induced cell division (Mn-CD) did not occur when the culture was in the exponential or death phase. The Mn-CD effect produced daughter cells proportionally reduced in size, pigmentation, and radioresistance but proportionally increased in activity and amount of the oxygen toxicity defense enzymes superoxide dismutase and catalase. In addition, the concentration of an Mn-CD-induced protein was found to remain high throughout the entire Mn-CD phase. It was also found that an untreated culture exhibited a growth curve characterized by a very rapid exponential-stationary transition and that cells which had just reached the early stationary phase were synchronous. Our results suggest the presence of an Mn(II)-sensitive mechanism for controlling cell division. The Mn-CD effect appears to be specific to the cation Mn(II) and the radioresistant bacteria, deinococci.
- OSTI ID:
- 7004605
- Journal Information:
- Journal of Bacteriology; (USA), Vol. 172:4; ISSN 0021-9193
- Country of Publication:
- United States
- Language:
- English
Similar Records
Superoxide dismutase and catalase conjugated to polyethylene glycol increases endothelial enzyme activity and oxidant resistance
Investigation of the Highly Active Manganese Superoxide Dismutase from Saccharomyces cerevisiae
Related Subjects
54 ENVIRONMENTAL SCIENCES
MANGANESE
BIOLOGICAL EFFECTS
MICROCOCCUS
CELL DIVISION
RADIOSENSITIVITY
CATALASE
CELL CYCLE
DOSE-RESPONSE RELATIONSHIPS
SUPEROXIDE DISMUTASE
ULTRAVIOLET RADIATION
BACTERIA
ELECTROMAGNETIC RADIATION
ELEMENTS
ENZYMES
METALS
MICROORGANISMS
OXIDOREDUCTASES
PEROXIDASES
RADIATIONS
TRANSITION ELEMENTS
560300* - Chemicals Metabolism & Toxicology
540130 - Environment
Atmospheric- Radioactive Materials Monitoring & Transport- (1990-)