Regulation of carcinogens
Journal Article
·
· Risk Anal.; (United States)
A procedure, suitable for regulatory use, is proposed for estimating individual and societal risks of carcinogenic materials by using information on interspecies comparisons of carcinogenic potency. The consistent treatment of uncertainties allows evaluation of confidence limits and hence regulatory measures of risk which incorporate safety factors and incentives for better information. Numerical examples are given, together with discussion of the treatment of undetected carcinogens. Applications of the procedure to setting priorities for carcinogenicity testing and to product substitution are mentioned.
- Research Organization:
- Harvard Univ., Cambridge, MA
- OSTI ID:
- 7002782
- Journal Information:
- Risk Anal.; (United States), Vol. 1:1
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CARCINOGENS
DOSE-RESPONSE RELATIONSHIPS
RISK ASSESSMENT
ACRYLONITRILE
AFLATOXIN
CALCULATION METHODS
PROBABILITY
REGULATIONS
SACCHARIN
ANTIGENS
AZOLES
HETEROCYCLIC COMPOUNDS
MATERIALS
NITRILES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
THIAZOLES
TOXIC MATERIALS
TOXINS
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
CARCINOGENS
DOSE-RESPONSE RELATIONSHIPS
RISK ASSESSMENT
ACRYLONITRILE
AFLATOXIN
CALCULATION METHODS
PROBABILITY
REGULATIONS
SACCHARIN
ANTIGENS
AZOLES
HETEROCYCLIC COMPOUNDS
MATERIALS
NITRILES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
THIAZOLES
TOXIC MATERIALS
TOXINS
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)