Studies of human mutation rates, December 1, 1985--November 30, 1986

Technical Report · Wed May 01 00:00:00 EDT 1985

OSTI ID:6998178

Neel, J V

This program seeks to quantify native human mutation rates and to determine how man's activities may affect these rates. The program is divided into six tasks, i.e. The American Indian mutation rate, monitoring populations for frequency of mutation by electrophoresis of blood proteins, application of molecular biological approaches to the detection and study of mutational events in human populations, development of two-dimensional electrophoresis for identification of mutant proteins, co-operative program with the Radiation Effects Research Foundation in Hiroshima and Nagasaki, Japan, and statistical problems associated with the estimation of mutation rates. Progress of each of the above tasks is related in detail. (DT)

• Research Organization: Michigan Univ., Ann Arbor (USA). Dept. of Human Genetics
• DOE Contract Number: AC02-82ER60089
• OSTI ID: 6998178
• Report Number(s): DOE/ER-60089-2; ON: DE88009918
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
A-BOMB SURVIVORS
GENE MUTATIONS
ALGORITHMS
DESIGN
TWO-DIMENSIONAL ELECTROPHORESIS
MAN
MUTATION FREQUENCY
STATISTICS
IMAGE PROCESSING
AMERICAN INDIANS
ANTHROPOLOGY
ELECTROPHORESIS
GENETIC VARIABILITY
HUMAN POPULATIONS
INTERNATIONAL COOPERATION
JAPAN
NEONATES
PROGRESS REPORT
RFLPS
USA
ANIMALS
ASIA
BIOLOGICAL VARIABILITY
COOPERATION
DOCUMENT TYPES
MAMMALS
MATHEMATICAL LOGIC
MATHEMATICS
MINORITY GROUPS
MUTATIONS
NORTH AMERICA
POPULATIONS
PRIMATES
PROCESSING
VERTEBRATES
560120* - Radiation Effects on Biochemicals
Cells
& Tissue Culture
560151 - Radiation Effects on Animals- Man
550200 - Biochemistry
550400 - Genetics