Long-term bioeffects of 435-MHz radiofrequency radiation on selected blood-borne endpoints in cannulated rats. Volume 2. Plasma ACTH (adrenocorticotropic hormone) and plasma corticosterone. Final report, 20 August 1984-16 February 1986

Technical Report · Sat Aug 01 00:00:00 EDT 1987

OSTI ID:6997929

Popovic, V P; Toler, J C; Bonasera, S J; Popovic, P P; Honeycutt, C B

Two hundred adult male white rats with chronically implanted aortic cannulas were randomly divided into two groups. Animals in the first group were exposed to low-level (1.0 mW/cm2) pulsed-wave 435-MHz radiofrequency radiation (RFR) for approximately 22 h daily, 7 days each week, for 6 months. Animals in the second group were maintained under identical conditions, but were not radiated. The cannulas were used to draw microsamples (0.3 mL) of aortic blood from the unrestrained, unanesthetized rats on a cyclic schedule. Plasma adrenocorticotropic hormone (ACTH) and plasma corticosterone concentrations were determined by radioimmunoassays hormone (ACTH) and plasma corticosterone concentrations were determined by radioimmunoassays. Statistical analysis of the results did not indicate increased plasma ACTH and plasma corticosterone concentrations in exposed animals when compared to sham-exposed animals. Exposure to this low-level radiofrequency environment did not induce stresses that were manifested as an alteration in plasma hormones.

• Research Organization: Georgia Inst. of Tech., Atlanta, GA (USA). Research Inst.
• OSTI ID: 6997929
• Report Number(s): AD-A-217065/2/XAB
• Resource Relation: Other Information: See also Volume 3, AD-B183 863
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
CORTICOSTERONE
BIOSYNTHESIS
RADIOWAVE RADIATION
BIOLOGICAL EFFECTS
AORTA
BLOOD PLASMA
MHZ RANGE 100-1000
PROGRESS REPORT
RADIOIMMUNOASSAY
RATS
ADRENAL HORMONES
ANIMALS
ARTERIES
BIOASSAY
BIOLOGICAL MATERIALS
BLOOD
BLOOD VESSELS
BODY
BODY FLUIDS
CARDIOVASCULAR SYSTEM
CORTICOSTEROIDS
DIAGNOSTIC TECHNIQUES
DOCUMENT TYPES
ELECTROMAGNETIC RADIATION
FREQUENCY RANGE
GLUCOCORTICOIDS
HYDROXY COMPOUNDS
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
KETONES
MAMMALS
MATERIALS
MHZ RANGE
ORGANIC COMPOUNDS
ORGANS
PREGNANES
RADIATIONS
RADIOASSAY
RADIOIMMUNODETECTION
RADIOIMMUNOLOGY
RODENTS
STEROIDS
SYNTHESIS
TRACER TECHNIQUES
VERTEBRATES
560400* - Other Environmental Pollutant Effects
550201 - Biochemistry- Tracer Techniques