Practical dosimetric aspects of blood and blood product irradiation

Journal Article · Mon Sep 01 00:00:00 EDT 1986 · Transfusion (Philadelphia); (United States)

DOI:https://doi.org/10.1046/j.1537-2995.1986.26587020125.x· OSTI ID:6989758

Fearon, T C; Luban, N L

The method of choice to reduce susceptibility to transfusion-transmitted graft-versus-host disease is irradiation of allogenic blood and blood products for transfusion to immunosuppressed recipients. Optimal irradiation requires delivery of a known and homogeneous absorbed dose. The use of absorbed dose in air measured at the center of the irradiation volume without proper compensation for sample absorption can lead to approximately 20 percent underexposure. A lucite cylinder was used to provide the delivery of a homogeneous irradiation dose to blood products of different volumes by allowing rotation of the product.

• Research Organization: Children's Hospital National Medical Center, Washington, DC
• OSTI ID: 6989758
• Journal Information: Transfusion (Philadelphia); (United States), Vol. 5
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BLOOD
IRRADIATION PROCEDURES
GRAFT-HOST REACTION
IMMUNOSUPPRESSION
IN VITRO
IRRADIATION
RADIATION DOSES
TRANSFUSIONS
BIOLOGICAL MATERIALS
BODY FLUIDS
DOSES
MATERIALS
THERAPY
560151* - Radiation Effects on Animals- Man
560130 - Radiation Effects on Microorganisms