Hyperbaric oxygen in the treatment of radiation-induced optic neuropathy

Journal Article · Fri Aug 01 00:00:00 EDT 1986 · Ophthalmology (Rochester, Minn.); (United States)

DOI:https://doi.org/10.1016/S0161-6420(86)33617-0· OSTI ID:6989745

Guy, J; Schatz, N J

Four patients with radiation-induced optic neuropathies were treated with hyperbaric oxygen. They had received radiation therapy for treatment of pituitary tumors, reticulum cell sarcoma, and meningioma. Two presented with amaurosis fugax before the onset of unilateral visual loss and began hyperbaria within 72 hours after development of unilateral optic neuropathy. Both had return of visual function to baseline levels. The others initiated treatment two to six weeks after visual loss occurred in the second eye and had no significant improvement of vision. Treatment consisted of daily administration of 100% oxygen under 2.8 atmospheres of pressure for 14-28 days. There were no medical complications of hyperbaria. While hyperbaric oxygen is effective in the treatment of radiation-induced optic neuropathy, it must be instituted within several days of deterioration in vision for restoration of baseline function.

• Research Organization: Univ. of Florida, Gainesville
• OSTI ID: 6989745
• Journal Information: Ophthalmology (Rochester, Minn.); (United States), Vol. 8
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
62 RADIOLOGY AND NUCLEAR MEDICINE
EYES
POST-IRRADIATION THERAPY
RADIOTHERAPY
SIDE EFFECTS
OXYGEN
PATIENTS
RADIATION INJURIES
VISION
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
ELEMENTS
FACE
HEAD
INJURIES
MEDICINE
NONMETALS
NUCLEAR MEDICINE
ORGANS
RADIATION EFFECTS
RADIOLOGY
SENSE ORGANS
THERAPY
560151* - Radiation Effects on Animals- Man
550603 - Medicine- External Radiation in Therapy- (1980-)