Prolongation of experimental islet transplant survival by fractionated splenic irradiation. [Dogs]

Journal Article · Mon Dec 01 00:00:00 EST 1980 · Transplant. Soc., Int. Cong., Proc.; (United States)

OSTI ID:6983769

Kolb, E; Casanova, M; Largiader, F

Experiments designed to delay the rejection of intrasplenic pancreatic fragment allotransplants in dogs showed increased transplant survival times from 3.1 days (controls) to 5.5 days with fractionated splenic irradiation and to 7.5 days with combined local irradiation and immunosuppressive chemotherapy. Drug treatment alone had no beneficial effect.

• Research Organization: University Hospital, Zurich, Switzerland
• OSTI ID: 6983769
• Journal Information: Transplant. Soc., Int. Cong., Proc.; (United States), Vol. 12:4
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANTIMETABOLITES
SIDE EFFECTS
ENDOXAN
IMMUNOSUPPRESSION
RADIOINDUCTION
PANCREAS
TISSUE EXTRACTS
TRANSPLANTS
SPLEEN
BIOLOGICAL RADIATION EFFECTS
X RADIATION
DOGS
FRACTIONATED IRRADIATION
ALKYLATING AGENTS
ANIMALS
ANTIMITOTIC DRUGS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BODY
DIGESTIVE SYSTEM
DRUGS
ELECTROMAGNETIC RADIATION
ENDOCRINE GLANDS
GLANDS
IONIZING RADIATIONS
IRRADIATION
MAMMALS
MATERIALS
ORGANS
RADIATION EFFECTS
RADIATIONS
VERTEBRATES
560152* - Radiation Effects on Animals- Animals