Hepatic arterial perfusion scintigraphy with Tc-99m-MAA: use of a totally implanted drug delivery system

Journal Article · Sun Jul 01 00:00:00 EDT 1984 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.152.1.6233632· OSTI ID:6983033

Ziessman, H A; Thrall, J H; Yang, P J; Walker, S C; Cozzi, E A; Niederhuber, J E; Gyves, J W; Ensminger, W D; Tuscan, M C

Tc-99m-MAA hepatic arterial perfusion scintigraphy (HAPS) using a totally implanted drug delivery system was employed for hepatic arterial chemotherapy in 147 patients (335 studies). Complete perfusion of the involved liver was seen in 88% of patients initially and remained good on follow-up. A significant decrease in hepatic and/or extrahepatic perfusion associated with a hot spot at the tip of the catheter indicated hepatic arterial thrombosis. Extrahepatic perfusion was seen in 14% of cases, usually in the distribution of the stomach, small bowel, and spleen. Significant symptoms of drug toxicity were seen in 70% of patients with extrahepatic perfusion, compared to 19% of those without it.

• Research Organization: Univ. of Michigan Medical Center, Ann Arbor
• OSTI ID: 6983033
• Journal Information: Radiology; (United States), Vol. 152:1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
SCINTISCANNING
NEOPLASMS
CHEMOTHERAPY
TECHNETIUM 99
ALBUMINS
ISOMERIC NUCLEI
LIVER
MICROSPHERES
PATIENTS
PERFUSED TISSUES
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
PROTEINS
RADIOISOTOPE SCANNING
RADIOISOTOPES
TECHNETIUM ISOTOPES
THERAPY
TISSUES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics