Iodine-131 uptake in inflammatory lung disease: a potential pitfall in treatment of thyroid carcinoma
A mixed differentiated thyroid carcinoma was found in a small asymptomatic nodule in a 44-yr-old woman with recurrent chest infections and bronchiectasis. After total thyroidectomy and 162 mCi (6 GBq) radioiodine ablation there was uptake in the thyroid remnant and in both lungs, interpreted as lung metastases. In 2 years she received further three 162 mCi (6 GBq) doses of /sup 131/I, as scans showed very similar lung activity. Another scan, during thyroxin suppression, showed again activity in the lungs. A 47-yr-old male patient with similar respiratory disease and no history of thyroid disorder volunteered to undergo radioiodine scan while on triiodothyronine suppression. His scan, too, showed concentration in the lungs. The female patient died 7 years after the diagnosis of lung thyroid metastases was made. No metastasis was found at autopsy. Radioiodine lung uptake may occur in patients with chronic inflammatory lung disease, presenting a potential diagnostic pitfall in patients with differentiated thyroid carcinoma.
- Research Organization:
- Prince of Wales Hospital, Randwick (Australia)
- OSTI ID:
- 6973556
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 29:5
- Country of Publication:
- United States
- Language:
- English
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IODINE 131
UPTAKE
LUNGS
NEOPLASMS
RADIOISOTOPE SCANNING
RESPIRATORY SYSTEM DISEASES
DIAGNOSIS
THYROID
CARCINOMAS
METASTASES
PNEUMONIA
THYROIDECTOMY
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DISEASES
ENDOCRINE GLANDS
GLANDS
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPES
MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
RESPIRATORY SYSTEM
SURGERY
550601* - Medicine- Unsealed Radionuclides in Diagnostics