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Title: Method and apparatus for fringe-scanning chromosome analysis

Patent ·
OSTI ID:6966114

Apparatus and method are provided for analyzing sub-micron-sized features of microscopic particles. Two central features of the invention are (1) constraining microscopic particles to flow with substantially constant orientation through a predetermined interference fringe pattern, and (2) estimating particle structure by analyzing its fringe profile. The invention allows nearly an order of magnitude higher resolution of chromosome structure than possible with currently available flow system techniques. The invention allows rapid and accurate flow karyotyping of chromosomes.

DOE Contract Number:
W-7405-ENG-48
Assignee:
Dept. of Energy
Application Number:
ON: DE84010873
OSTI ID:
6966114
Resource Relation:
Other Information: Portions are illegible in microfiche products
Country of Publication:
United States
Language:
English