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Title: The clinical value of bone and gallium scintigraphy for soft-tissue sarcomas of the extremities

Journal Article · · J. Bone Jt. Surg., Am. Vol.; (United States)
OSTI ID:6965455

In a prospective study of forty-five patients, we evaluated the usefulness of bone and gallium scintigraphy prior to definitive surgery for a soft-tissue sarcoma in an extremity. Bone scintigraphy provides a baseline for staging and often reveals periosteal invasion that is not detected by routine radiographs. Blood-pool scintigraphy with bone tracers is very sensitive for a diagnosis of malignant disease. Gallium scintigraphy appeared to be a reliable preoperative indicator of malignant disease of soft tissue (sensitivity, 85 per cent; specificity, 92 per cent) and was useful for detecting the infrequent occult, non-pulmonary metastasis. Combined gallium and bone scintigraphy with blood-pool imaging provided a reliable prediction of the presence or absence of a malignant lesion in patients with a soft-tissue mass in an extremity. We recommend that bone and gallium scintigraphy be routinely used in the initial clinical staging of soft-tissue sarcomas.

Research Organization:
Department of Radiology, University of Chicago Hospitals and Clinics, Pritzker School of Medicine, Illinois
OSTI ID:
6965455
Journal Information:
J. Bone Jt. Surg., Am. Vol.; (United States), Vol. 66:3
Country of Publication:
United States
Language:
English