Comparison of contrast x-ray biplane cineangiography and technetium-99m radionuclide scans for measurement of ventricular volumes in human autopsy hearts

Journal Article · Sat Nov 01 00:00:00 EST 1986 · Am. Heart J.; (United States)

DOI:https://doi.org/10.1016/0002-8703(86)90317-0· OSTI ID:6965230

Palacios, I; Goldman, M; Aretz, T; Okada, R; Osbakken, M; Leavitt, M; Block, P C; Boucher, C

The area-length method is widely used in the determination of left ventricular volume. Although previous studies have reported that this technique overestimates true volume (TV), it is unknown whether this overestimation is the same at different volumes. In the present study, with the use of 10 postmortem human hearts, left ventricular volumes were determined by contrast x-ray biplane cine ventriculography (LVA), biplane radionuclide (LVR), and absolute-counts (LVC) technetium scans, and the results were correlated with TV. LVA correlated well with TV (r = 0.98). LVR correlated well with TV (r = 0.97), and LVR also correlated well with LVA (r = 0.96). Both area-length techniques (LVA and LVR) resulted in overestimation of TV with an upward shift of the regression line of 30.4ml +/- 3.8 (SEM) for LVA and 28.5 +/- 4.4 for LVR. The percentage of overestimation error was significantly greater at smaller left ventricular volumes (error = 33% at TV = 30ml and 10% at TV = 100ml, p less than 0.001). LVC correlated well with TV (r = 0.99), TVA, and LVR but underestimated TV. Thus left ventricular volumes can be reliably obtained from LVR and LVA by means of the area-length method and from LVC. When the area-length method is utilized, the percentage of error in the determination of left ventricular volume is proportional to 1/TV.

• Research Organization: Massachusetts General Hospital, Boston
• OSTI ID: 6965230
• Journal Information: Am. Heart J.; (United States), Vol. 5
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
HEART
BIOMEDICAL RADIOGRAPHY
SCINTISCANNING
VOLUME
AUTOPSY
ERRORS
TECHNETIUM 99
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
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