Electrospray ionization phenomena and the interface of capillary electrophoresis and mass spectrometry. [Quaternary phosphonium salts]

Conference · Wed Jun 01 00:00:00 EDT 1988

OSTI ID:6956822

Smith, R D; Barinaga, C J; Udseth, H R

Recently a new electrospray ionization interface for capillary electrophoresis-mass spectroscopy (CE-MS) has been developed. The interface uses a sheath flow of liquid to make electrical contact at the CZE terminus, thus defining both the CZE and electrospray field gradients. Ions created by the ESI process are sampled through a 1 mm nozzle into a region mechanically pumped at 50 L/s using a single-stage roots blower. The ions entering this region are sampled through a 2 mm dia skimmer orifice located 0.5 cm behind the nozzle orifice. Ions passing through the skimmer enter a radio frequency focusing quadrupole. This region is pumped by a cryopump. A mixture of four quaternary phosphonium salts is used to illustrate capillary electrophoresis separations with mass spectroscopy and their uses. 2 figs.

• Research Organization: Pacific Northwest Lab., Richland, WA (USA)
• DOE Contract Number: AC06-76RL01830
• OSTI ID: 6956822
• Report Number(s): PNL-SA-15664; CONF-8806199-4; ON: DE88014080
• Resource Relation: Conference: 36. annual conference on mass spectrometry and allied topics, San Francisco, CA, USA, 6 Jun 1988
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
ELECTROPHORESIS
MASS SPECTROSCOPY
ORGANIC PHOSPHORUS COMPOUNDS
SEPARATION PROCESSES
CAPILLARIES
IONIZATION
MIXTURES
SPRAYS
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
DISPERSIONS
ORGANIC COMPOUNDS
ORGANS
SPECTROSCOPY
400102* - Chemical & Spectral Procedures