Atlas generated generalized ROIs for use in functional neuroimaging

Conference · Mon Aug 01 00:00:00 EDT 1994 · IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States)

OSTI ID:6906798

Thurfjell, L ^[1]; Bohm, C ^[2]

---

1. Uppsala Univ., Stockholm (Sweden). Dept. of Neuroradiology and Clinical Neurophysiology
2. Univ. of Stockholm (Sweden). Dept. of Physics

The interpretation of functional neuroimaging data can, in many cases, be facilitated by comparison with simulated data corresponding to the measuring situation. A computerized brain atlas is used to provide information regarding the spatial extent of the object being imaged. This knowledge combined with information about the resolution of the imaging device expressed as point spread functions is used to calculate a simulated image of the object. The simulated image can be regarded as a generalized region of interest (ROI) containing information of the object as viewed by the specific instrument. Generalized ROIs are used to automatically determine boundaries or ordinary ROIs and to provide recovery coefficients to compensate for partial volume effects. Simulations can also be used to generate three-dimensional data sets where different activity levels have been assigned to different anatomical structures. These methods are presented in this paper and some experimental results are shown.

• OSTI ID: 6906798
• Report Number(s): CONF-931051-; CODEN: IETNAE
• Journal Information: IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States), Vol. 41:4PT1; Conference: NSS-MIC '93: nuclear science symposium and medical imaging conference, San Francisco, CA (United States), 30 Oct - 6 Nov 1993; ISSN 0018-9499
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BRAIN
POSITRON COMPUTED TOMOGRAPHY
SPATIAL RESOLUTION
IMAGE PROCESSING
OPTIMIZATION
BODY
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
EMISSION COMPUTED TOMOGRAPHY
NERVOUS SYSTEM
ORGANS
PROCESSING
RESOLUTION
TOMOGRAPHY
550601* - Medicine- Unsealed Radionuclides in Diagnostics