Effect of positive pleural pressure on left ventricular performance
Abstract
A sudden increase in pleural pressure such as coughing or a valsalva maneuver causes a transient increase in left ventricular stroke volume but the mechanism is not known. To help understand this phenomenon we studied 7 normal volunteers during spontaneous breathing and when breathing under positive pleural pressure. The positive pressure was developed by expiring against a 24cm H/sub 2/O threshold load. Radionuclide ventriculopgraphy using a double gating technique as performed. Image data were acquired during the cardiac cycles occurring during positive pleural pressure by means of a pressure transducer coupled to an EKG gate. They were compared to data acquired by EKG gating alone under quiet respiration as control. Results are shown for end diastolic (EDC), end systolic (ESC) and stroke counts (SC) and are expressed as % change from control for each parameter. The authors conclude that a transient increase in positive pleural pressure comparable to that reached during forceful coughing increases stroke volume and cardiac output through a combination of increased end diastolic volume with a lesser increase in end systolic volume. This effect was seen in the absence of any change in cardiac rhythm or rate.
- Authors:
- Publication Date:
- Research Org.:
- The Johns Hopkins Medical Institutions, Baltimore, MD
- OSTI Identifier:
- 6859342
- Report Number(s):
- CONF-840619-
Journal ID: CODEN: JNMEA; TRN: 87-019053
- Resource Type:
- Conference
- Journal Name:
- J. Nucl. Med.; (United States)
- Additional Journal Information:
- Journal Volume: 25:5; Conference: 31. annual meeting of the Society of Nuclear Medicine, Los Angeles, CA, USA, 5 Jun 1984
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 62 RADIOLOGY AND NUCLEAR MEDICINE; CAT SCANNING; IMAGE PROCESSING; EMISSION COMPUTED TOMOGRAPHY; HEART; DYNAMIC FUNCTION STUDIES; RADIOCARDIOGRAPHY; BIOMEDICAL RADIOGRAPHY; COMPARATIVE EVALUATIONS; DATA ACQUISITION; PERFORMANCE; RADIOISOTOPE SCANNING; RADIONUCLIDE KINETICS; RESPIRATION; SCINTISCANNING; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; BODY; CARDIOGRAPHY; CARDIOVASCULAR SYSTEM; COMPUTERIZED TOMOGRAPHY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; MEDICINE; NUCLEAR MEDICINE; ORGANS; PROCESSING; RADIOLOGY; TOMOGRAPHY; 551001* - Physiological Systems- Tracer Techniques; 550601 - Medicine- Unsealed Radionuclides in Diagnostics
Citation Formats
Natarajan, T K, Karam, M, Wise, R, and Wagner, H N. Effect of positive pleural pressure on left ventricular performance. United States: N. p., 1984.
Web.
Natarajan, T K, Karam, M, Wise, R, & Wagner, H N. Effect of positive pleural pressure on left ventricular performance. United States.
Natarajan, T K, Karam, M, Wise, R, and Wagner, H N. 1984.
"Effect of positive pleural pressure on left ventricular performance". United States.
@article{osti_6859342,
title = {Effect of positive pleural pressure on left ventricular performance},
author = {Natarajan, T K and Karam, M and Wise, R and Wagner, H N},
abstractNote = {A sudden increase in pleural pressure such as coughing or a valsalva maneuver causes a transient increase in left ventricular stroke volume but the mechanism is not known. To help understand this phenomenon we studied 7 normal volunteers during spontaneous breathing and when breathing under positive pleural pressure. The positive pressure was developed by expiring against a 24cm H/sub 2/O threshold load. Radionuclide ventriculopgraphy using a double gating technique as performed. Image data were acquired during the cardiac cycles occurring during positive pleural pressure by means of a pressure transducer coupled to an EKG gate. They were compared to data acquired by EKG gating alone under quiet respiration as control. Results are shown for end diastolic (EDC), end systolic (ESC) and stroke counts (SC) and are expressed as % change from control for each parameter. The authors conclude that a transient increase in positive pleural pressure comparable to that reached during forceful coughing increases stroke volume and cardiac output through a combination of increased end diastolic volume with a lesser increase in end systolic volume. This effect was seen in the absence of any change in cardiac rhythm or rate.},
doi = {},
url = {https://www.osti.gov/biblio/6859342},
journal = {J. Nucl. Med.; (United States)},
number = ,
volume = 25:5,
place = {United States},
year = {Sun Jan 01 00:00:00 EST 1984},
month = {Sun Jan 01 00:00:00 EST 1984}
}