Electron-microscopic and autoradiographic study of bronchioalveolar lavage cells in nonspecific inflammation of the lungs
The authors continue the quantitative analysis of endopulmonary cytograms by making an ultrastructural and autoradiographic study of lavage cells in chronic nonspecific inflammatory diseases of the lungs. Semithin sections of lavage cells incubated with tritium-uridine were prepared by light-microscopic authoradiography, then stained with azure II for the counting of the density and labeling index of the lavage cells. Ultrastructural analysis showed marked heterogeneity of the macrophage population in the bronchoalveolar washings from patients with chronic inflammation of the lungs. It is shown that the process of activation of the macrophagal system can take place quite rapidly and can be induced by several different factors which are discussed in the paper.
- OSTI ID:
- 6858868
- Journal Information:
- Bull. Exp. Biol. Med. (Engl. Transl.); (United States), Vol. 101:1
- Country of Publication:
- United States
- Language:
- English
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ANIMAL CELLS
AUTORADIOGRAPHY
INFLAMMATION
PATIENTS
LUNGS
BIOCHEMISTRY
BIOLOGICAL EFFECTS
BIOLOGICAL FUNCTIONS
CELL CULTURES
CYTOLOGY
CYTOPLASM
LAVAGE
MORPHOLOGY
ORGANOIDS
TRANSCRIPTION
TRITIUM COMPOUNDS
ULTRASTRUCTURAL CHANGES
URIDINE
AZINES
BIOLOGY
BODY
CELL CONSTITUENTS
CHEMISTRY
FUNCTIONS
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
LABELLED COMPOUNDS
MORPHOLOGICAL CHANGES
NUCLEOSIDES
NUCLEOTIDES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
PYRIMIDINES
RESPIRATORY SYSTEM
RIBOSIDES
SYMPTOMS
URACILS
550301* - Cytology- Tracer Techniques
550901 - Pathology- Tracer Techniques