Greater left cerebral hemispheric metabolism in bulimia assessed by positron emission tomography

Journal Article · Thu Mar 01 00:00:00 EST 1990 · American Journal of Psychiatry; (USA)

OSTI ID:6854711

Wu, J C; Hagman, J; Buchsbaum, M S; Blinder, B; Derrfler, M; Tai, W Y; Hazlett, E; Sicotte, N ^[1]

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1. Univ. of California, Irvine (USA)

Eight women with bulimia and eight age- and sex-matched normal control subjects were studied with positron emission tomography using (18F)-fluorodeoxyglucose (FDG) as a tracer of brain metabolic rate. Subjects performed a visual vigilance task during FDG uptake. In control subjects, the metabolic rate was higher in the right hemisphere than in the left, but patients with bulimia did not have this normal asymmetry. Lower metabolic rates in the basal ganglia, found in studies of depressed subjects, and higher rates in the basal ganglia, reported in a study of anorexia nervosa, were not found. This is consistent with the suggestion that bulimia is a diagnostic grouping distinct from these disorders.

• OSTI ID: 6854711
• Journal Information: American Journal of Psychiatry; (USA), Vol. 147:3; ISSN 0002-953X
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
BRAIN
POSITRON COMPUTED TOMOGRAPHY
GLUCOSE
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FLUORINE 18
TRACER TECHNIQUES
ALDEHYDES
BETA DECAY RADIOISOTOPES
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ISOTOPE APPLICATIONS
ISOTOPES
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MONOSACCHARIDES
NERVOUS SYSTEM
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANS
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