Irrigating solutions used in arthroscopy and their effect on articular cartilage. An in vivo study
The effect of arthroscopic irrigating solutions on articular cartilage was determined by the use of an animal model. Rabbit knee joints were irrigated continuously for two hours with either normal saline, Ringer's lactate, or sterile water. Subsequently, the rate of incorporation of /sup 35/SO/sub 4/ by articular cartilage was used to measure the effect of the irrigants on chondrocyte metabolism. In addition, the irrigated groups were compared to an unirrigated control group. There was no significant difference in /sup 35/SO/sub 4/ incorporation between the groups. This suggested that none of the irrigating solutions used in this study adversely affected articular cartilage function. On the basis of these findings, it appears that normal saline, Ringer's lactate, and sterile water can be safely used as irrigating solutions during most arthroscopic procedures.
- Research Organization:
- Madigan Army Medical Center, Tacoma, WA
- OSTI ID:
- 6846684
- Journal Information:
- Orthopedics (Thorofare, N.J.); (United States), Vol. 11
- Country of Publication:
- United States
- Language:
- English
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62 RADIOLOGY AND NUCLEAR MEDICINE
BONE JOINTS
SURGERY
CARTILAGE
BIOLOGICAL FUNCTIONS
ISOTONIC SOLUTIONS
BIOLOGICAL EFFECTS
SULFATES
METABOLISM
BIOLOGICAL MODELS
COMPARATIVE EVALUATIONS
IN VIVO
RABBITS
SULFUR 35
TRACER TECHNIQUES
ANIMAL TISSUES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CONNECTIVE TISSUE
DAYS LIVING RADIOISOTOPES
DISPERSIONS
EVEN-ODD NUCLEI
FUNCTIONS
ISOTOPE APPLICATIONS
ISOTOPES
LIGHT NUCLEI
MAMMALS
MEDICINE
MIXTURES
NUCLEI
ORGANS
OXYGEN COMPOUNDS
RADIOISOTOPES
SKELETON
SOLUTIONS
SULFUR COMPOUNDS
SULFUR ISOTOPES
TISSUES
VERTEBRATES
550201* - Biochemistry- Tracer Techniques
550600 - Medicine