A 3D HIDAC-PET camera with sub-millimeter resolution for imaging small animals
- Oxford Positron Systems (United Kingdom)
A HIDAC-PET camera consisting essentially of 5 million 0.5 mm gas avalanching detectors has been constructed for small-animal imaging. The particular HIDAC advantage--a high 3D spatial resolution--has been improved to 0.95 mm fwhm and to 0.7 mm fwhm when reconstructing with 3D-OSEM methods incorporating resolution recovery. A depth-of-interaction resolution of 2.5 mm is implicit, due to the laminar construction. Scatter-corrected sensitivity, at 8.9 cps/kBq (i.e. 0.9%) from a central point source, or 7.2 cps/kBq (543 cps/kBq/cm{sup 3}) from a distributed (40 mm diameter, 60 mm long) source is now much higher than previous, and other, work. A field-of-view of 100 mm (adjustable to 200 mm) diameter by 210 mm axially permits whole-body imaging of small animals, containing typically 4MBqs of activity, at 40 kcps of which 16% are random coincidences, with a typical scatter fraction of 44%. Throughout the field-of-view there are no positional distortions and relative quantitation is uniform to {+-} 3.5%, but some variation of spatial resolution is found. The performance demonstrates that HIDAC technology is quite appropriate for small-animal PET cameras.
- OSTI ID:
- 684493
- Report Number(s):
- CONF-981110-; ISSN 0018-9499; TRN: 99:010045
- Journal Information:
- IEEE Transactions on Nuclear Science, Vol. 46, Issue 3Pt2; Conference: 1998 IEEE nuclear science symposium and medical imaging conference, Toronto (Canada), 10-12 Nov 1998; Other Information: PBD: Jun 1999
- Country of Publication:
- United States
- Language:
- English
Similar Records
A high resolution animal PET scanner using compact PS-PMT detectors
PET optimization for improved assessment and accurate quantification of {sup 90}Y-microsphere biodistribution after radioembolization