Predicting splenic abnormality in Hodgkin disease using volume response to epinephrine administration

Journal Article · Tue Jun 01 00:00:00 EDT 1982 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.143.3.6979062· OSTI ID:6844305

Rosen, P R; Lasher, J C; Weiland, F L; Kopp, D T

The change in relative splenic volume following epinephrine administration was used to determine splenic abnormality noninvasively. Selective splenic imaging was accomplished with /sup 99m/Tc-labeled heat-treated red blood cells, an LFOV gamma camera, a 30/sup 0/ bilateral rotating slant hole collimator, and bilateral slant hole tomographic software. Relative splenic volumes were plotted over time, and correlated with clinical and histologic data. Eight patients with Hodgkin disease and other lymphomas were examined. Volume response to epinephrine appears to be significantly less in abnormal spleens, and may serve to identify patients with unequivocally normal spleens prior to treatment.

• Research Organization: Air Force Medical Center, Lackland AFB, TX
• OSTI ID: 6844305
• Journal Information: Radiology; (United States), Vol. 143:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ADRENALINE
BIOLOGICAL EFFECTS
SPLEEN
EMISSION COMPUTED TOMOGRAPHY
VOLUME
ERYTHROCYTES
GAMMA CAMERAS
HODGKINS DISEASE
ISOMERIC NUCLEI
PATIENTS
PHANTOMS
PYROPHOSPHATES
TECHNETIUM 99
TECHNETIUM OXIDES
ADRENAL HORMONES
AUTONOMIC NERVOUS SYSTEM AGENTS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
CAMERAS
CARDIOTONICS
CARDIOVASCULAR AGENTS
CHALCOGENIDES
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
HORMONES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LYMPHOMAS
MATERIALS
MOCKUP
NEOPLASMS
NEUROREGULATORS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXIDES
OXYGEN COMPOUNDS
PHOSPHORUS COMPOUNDS
RADIOISOTOPES
STEROID HORMONES
STRUCTURAL MODELS
SYMPATHOMIMETICS
TECHNETIUM COMPOUNDS
TECHNETIUM ISOTOPES
TOMOGRAPHY
TRANSITION ELEMENT COMPOUNDS
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics