Effects of lead and mercury intoxications on evoked potentials

Journal Article · Fri Jan 01 00:00:00 EST 1988 · J. Toxicol., Clin. Toxicol.; (United States)

DOI:https://doi.org/10.3109/15563658808995401· OSTI ID:6822281

Lille, F; Hazemann, P; Garnier, R; Dally, S

Pattern reversal, brain stem auditory and somatosensory evoked potentials (PREPs, BAEPs, SEPs) have been recorded on 13 patients occupationally exposed to inorganic lead compounds, in 9 patients occupationally or accidentally exposed to inorganic mercury compounds and in 26 chronic alcoholics. The results were compared to those of a normal control group. Peripheral conduction velocities were decreased in lead exposed workers and in alcoholics, but not modified in the mercury exposed patients. In the three exposed groups, an amplitude increase (PREPs and upper limb SEP cortical components), more important in the mercury group and an increase of central conduction time in case of lower limb stimulation, could be interpreted as early signs of nervous cortical impairment.

• Research Organization: CHU Pitie Salpetriere, Paris (France)
• OSTI ID: 6822281
• Journal Information: J. Toxicol., Clin. Toxicol.; (United States), Vol. 26:1-2
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
LEAD
TOXICITY
MERCURY
NERVOUS SYSTEM DISEASES
OCCUPATIONAL EXPOSURE
DISEASES
ELEMENTS
METALS
560300* - Chemicals Metabolism & Toxicology