A pulsed-field gel electrophoresis map in the ataxia-telangiectasia region of chromosome 11q22. 3

Journal Article · Tue Mar 15 00:00:00 EST 1994 · Genomics; (United States)

DOI:https://doi.org/10.1006/geno.1994.1165· OSTI ID:6822182

Uhrhammer, N; Huo, Y; Gatti, R A ^[1]; Concannon, P ^[2]; Nakamura, Yusuke ^[3]

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1. Univ. of California, Los Angeles, CA (United States)
2. Virginia Mason Research Center, Seattle, WA (United States)
3. Cancer Institute, Tokyo (Japan)

The authors interest in isolating the gene(s) for ataxia-telangiectasia has prompted construction of a physical map of chromosome 11q22.3 using markers localized to this region by linkage analysis and/or hybrid cell panels. Twenty-two markers have been analyzed by pulsed-field gel electrophoresis. Nine of these markers form an [approximately]2-Mb long-range contiguous map. An average distance of 200 kb between probes in this map should facilitate the isolation of new cDNAs, anonymous probes, and YACs in an orderly way. 15 refs., 2 figs.

• OSTI ID: 6822182
• Journal Information: Genomics; (United States), Vol. 20:2; ISSN 0888-7543
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
CEREBELLUM
HEREDITARY DISEASES
HUMAN CHROMOSOMES
GENETIC MAPPING
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CHROMOSOMES
DISEASES
MAPPING
NERVOUS SYSTEM
ORGANS
550400* - Genetics