Comparative analysis of dioxins and furans by electron impact, high-resolution mass spectrometry and by electron capture, negative ionization, low-resolution mass spectrometry
Electron impact, high resolution mass spectrometry (HRMS) is currently the method of choice for the analysis of polychlorinated dibenso-p-dioxins and dibenzofurans (PCDD/F) because of its ability to detect PCDD/F in the presence of interfering compounds, such as polychlorinated biphenyls (PCB), which cannot be resolved by low resolution methods. The PDCC/F analyses may also be performed using electron capture, negative ionization (ECNI) low resolution mass spectrometry, providing extensive sample preparation is done to remove interferences. Before ECNI low resolution mass spectrometry (MS) can be accepted as a routine method for PCDD/F analysis, it is necessary to show that results generated by this method are comparable to those obtained by HRMS. Known mixtures and unknown air samples were analyzed by electron impact HRMS (Finnigan MAT 90 system) and by ECNI low resolution MS (Hewlett Packard 5985B). Both instruments were fitted with a gas chromatographic inlet. The PCDD/F concentrations determined by the two techniques compare favorably, typically within 20%. The major difference between these two methods is that the ECNI low resolution method shows poor sensitivity in detecting 2,3,7,8-tetrachlorodioxin. However, ECNI MS offers the advantage of lower detection limits (50-100 fg) than electron impact HRMS (0.1 to 0.5 pg). These results suggest that ECNI low resolution MS can be a simple, low cost alternative to the common high resolution methods used for PCDD/F analysis.
- Research Organization:
- Indiana Univ., Bloomington, IN (USA)
- OSTI ID:
- 6761512
- Report Number(s):
- PB-90-263054/XAB; CNN: EPA-R-812588
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
BENZOFURANS
MASS SPECTROSCOPY
DIOXIN
AIR POLLUTION
COMPARATIVE EVALUATIONS
ELECTRON CAPTURE
INTERFERENCE
RESOLUTION
SAMPLE PREPARATION
CAPTURE
FURANS
HETEROCYCLIC COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
POLLUTION
SPECTROSCOPY
540120* - Environment
Atmospheric- Chemicals Monitoring & Transport- (1990-)