Measurement of photon attenuation from different cardiac chambers

Keller, A M; Simon, T R; Malloy, C R; Dehmer, G J; Smitherman, T C

Title: Measurement of photon attenuation from different cardiac chambers

Full Record
Other Related Research

Abstract

Accounting for the attenuation (AT) of photons within cardiac chambers is crucial to accurate non-geometric volume determinations from gated blood pool scintigraphy. Previous techniques to determine AT for each patient have assumed an attenuation factor of 0.15/cm for Tc-99m, the value of water. To verify this, the authors determined the AT at various tissue distances (TD) in vivo. As a point source they used the balloon of a 5 French Swan-Ganz catheter which could reproducibly be filled with a constant amount of Tc-99m and could be placed within the left or right cardiac chambers. The exact location of the balloon, once inflated, and the TD from the balloon to the collimator of a small field-of-view Anger camera was determined using biplane orthogonal fluoroscopy. AT was determined by counting the inflated Tc-99m filled balloon in air and dividing that value by the counts of the same balloon within the heart. The authors positioned the balloon in the apex of the right and left ventricle, the ascending aorta and at the junction of the right atrium and inferior vena cava to give a total of 36 simultaneous observations of AT and TD. For our data the slope of the regression of themore »« less

Authors:: Keller, A M; Simon, T R; Malloy, C R; Dehmer, G J; Smitherman, T C

Publication Date:: Wed May 01 00:00:00 EDT 1985

Research Org.:: Div. of Cardiology and Dept. of Radiology, Univ. of Texas Health Science Center, Dallas, TX

OSTI Identifier:: 6759985

Report Number(s):: CONF-850611-
Journal ID: CODEN: JNMEA; TRN: 87-010717

Resource Type:: Conference

Journal Name:: J. Nucl. Med.; (United States)

Additional Journal Information:: Journal Volume: 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985

Country of Publication:: United States

Language:: English

Subject:: 62 RADIOLOGY AND NUCLEAR MEDICINE; HEART; SCINTISCANNING; PERFORMANCE; ATTENUATION; CAT SCANNING; GAMMA CAMERAS; LABELLED POOL TECHNIQUES; PHOTONS; SPATIAL RESOLUTION; TRANSMISSION; BODY; CAMERAS; CARDIOVASCULAR SYSTEM; COMPUTERIZED TOMOGRAPHY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; ELEMENTARY PARTICLES; ISOTOPE APPLICATIONS; MASSLESS PARTICLES; ORGANS; RADIOISOTOPE SCANNING; RESOLUTION; TOMOGRAPHY; TRACER TECHNIQUES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats


                    Keller, A M, Simon, T R, Malloy, C R, Dehmer, G J, and Smitherman, T C. Measurement of photon attenuation from different cardiac chambers.  United States: N. p., 1985. 
        Web.

Copy to clipboard


                    Keller, A M, Simon, T R, Malloy, C R, Dehmer, G J, & Smitherman, T C. Measurement of photon attenuation from different cardiac chambers.  United States.

Copy to clipboard


                    Keller, A M, Simon, T R, Malloy, C R, Dehmer, G J, and Smitherman, T C. 1985.  
        "Measurement of photon attenuation from different cardiac chambers".  United States.

Copy to clipboard


                    
@article{osti_6759985,

  title        = {Measurement of photon attenuation from different cardiac chambers},

  author       = {Keller, A M and Simon, T R and Malloy, C R and Dehmer, G J and Smitherman, T C},

  abstractNote = {Accounting for the attenuation (AT) of photons within cardiac chambers is crucial to accurate non-geometric volume determinations from gated blood pool scintigraphy. Previous techniques to determine AT for each patient have assumed an attenuation factor of 0.15/cm for Tc-99m, the value of water. To verify this, the authors determined the AT at various tissue distances (TD) in vivo. As a point source they used the balloon of a 5 French Swan-Ganz catheter which could reproducibly be filled with a constant amount of Tc-99m and could be placed within the left or right cardiac chambers. The exact location of the balloon, once inflated, and the TD from the balloon to the collimator of a small field-of-view Anger camera was determined using biplane orthogonal fluoroscopy. AT was determined by counting the inflated Tc-99m filled balloon in air and dividing that value by the counts of the same balloon within the heart. The authors positioned the balloon in the apex of the right and left ventricle, the ascending aorta and at the junction of the right atrium and inferior vena cava to give a total of 36 simultaneous observations of AT and TD. For our data the slope of the regression of the natural log of AT versus TD, when forced through zero, was 0.102, the calculated attenuation factor. The authors conclude that the attenuation factor that should be used for determining cardiac volumes with gated blood pool scans is 0.102/cm, not the value for water.},

  doi          = {},

  url          = {https://www.osti.gov/biblio/6759985},
  journal      = {J. Nucl. Med.; (United States)},
number       = ,

  volume       = 26:5,

  place        = {United States},

  year         = {Wed May 01 00:00:00 EDT 1985},

  month        = {Wed May 01 00:00:00 EDT 1985}

}

Copy to clipboard

Conference:

Other availability

Please see Document Availability for additional information on obtaining the full-text document. Library patrons may search WorldCat to identify libraries that hold this conference proceeding.

Save / Share:

Export Metadata

Save to My Library

Similar records in OSTI.GOV collections:

Direct determination of the attenuation coefficient for radionuclide volume measurements

Journal Article Keller, A; Simon, T; Smitherman, T; ... - J. Nucl. Med.; (United States)

Correcting for the attenuation of photons between the cardiac chambers and chest surface is crucial for accurate nongeometric ventricular volume determinations from equilibrium radionuclide angiograms. Previous techniques have assumed that the attenuation coefficient of water for /sup 99m/Tc (0.15/cm) should be used for this correction. In this study, this assumption was tested directly by measuring attenuation of the activity of a radioactive source within the right and left cardiac chambers. The balloon of a flow-directed catheter, filled with /sup 99m/Tc, was used as a source and its depth within the body was measured with biplane fluoroscopy. In ten patients, amore »« less
Left ventricular stroke volume determinations from radionuclide ventriculograms: the effects of photon attenuation

Journal Article Schwaiger, M; Ratib, O; Henze, E; ... - Radiology; (United States)

To improve the accuracy of scintigraphic ventricular volume determination, which is limited by photon attenuation between the heart and the gamma camera, a method was developed for directly measuring the photon attenuation of radioactivity delivered as a bolus through a Swan-Ganz catheter into the right atrium. Comparison of the count rate recovered from this bolus with the total ex vivo measured activity determined by imaging an aliquot of the administered activity allowed calculation of the attenuation factor. Left ventricular stroke volumes determined scintigraphically by the count method in gated blood pool studies and then corrected with this attention factor correlatedmore »« less
https://doi.org/10.1148/radiology.153.1.6473788
Multigated blood-pool tomography: new method for the assessment of left ventricular function

Journal Article Gill, J; Moore, R; Tamaki, N; ... - J. Nucl. Med.; (United States)

A technique for the semiautomatic calculation of left ventricular volumes from multigated blood-pool tomograms (MGBPT) was tested in a series of 12 patients undergoing contrast ventriculography within 48 hr of gated tomography. The parameters necessary for the calculation of volume were developed in a chest phantom study performed with a series of /sup 99m/Tc-filled balloons representing the right and left ventricles. The images were analyzed for volume using a percentage of peak count-threshold of the left ventricular balloon. This technique resulted in a correlation of r = 0.99 of the calculated to the true phantom volumes (y = 0.87x +more »« less
Experimental evaluation of Tc-99m RBC radionuclide ventriculography for detecting pericardial bleeding

Conference Bateman, T; Kass, R; Garcia, E; ... - J. Nucl. Med.; (United States)

Radionuclide activity within the pericardial (P) space, either localized or surrounding the cardiac chambers, indicates active (P) bleeding when gated equilibrium radionuclide ventriculography (RNV) is performed with Tc-99m-labeled RBCs. To evaluate the ability of RNV to detect and to quantify the amount of accumulated P blood, the authors developed a simulated P bleeding model. By subxyphoid incision, a balloon (BAL) was inserted into the P space of 6 dogs. Images were reviewed to determine the presence and appearance of the P blood pool. Background-subtracted radioactive counts within each detected P blood pool were compared to known volume as a countmore »« less
Determination of left-ventricular volume from first-pass kinetics of labeled red cells

Journal Article Harpen, M; Dubuisson, R; Head, G; ... - J. Nucl. Med.; (United States)

A mathematical model is presented for the dynamics of a bolus of /sup 99m/Tc labeled red blood cells through the left ventricle. It is used to correct for attenuation the count rate observed over the left ventricle during a conventional gated blood-pool study. The left-ventricular volumes are calculated from the corrected count rates and expressed as a percentage of total blood volume, or in absolute terms if a blood sample is obtained. The procedure is applied to a number of patients with nonvalvular cardiac disease. Cardiac volumes determined by the method are found to correlate well (r . 0.98) withmore »« less

Similar Records