Abnormal Tc-99m-MDP/GA-67 scan patterns in association with active chronic osteomyelitis

Tumeh, S S; Aliabadi, P; Weissman, B; McNeil, B J

Title: Abnormal Tc-99m-MDP/GA-67 scan patterns in association with active chronic osteomyelitis

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Abstract

In this study the authors reviewed data from 136 patients (pts) in order to refine the interpretive criteria used to diagnose active osteomyelitis (AOM) in patients with previous bone disease (e.g., old osteomyelitis, fractures, orthopedic devices excluding prostheses). They evaluated bone (Tc-99mMDP) and gallium 67 studies and obtained followup in all pts. AOM was diagnosed by surgery or biopsy and culture in 49 pts and was excluded by the same criteria in 16 pts. An additional 71 pts had the diagnosis excluded by followup clinical criteria. Five patterns were found. T1: abnormal Tc-99m-MDP, normal Ga-67. T2: diffuse increased uptake of both radiopharmaceuticals with Tc-99m-MDP greater than Ga-67. T3: different geographic distribution, but similar intensities of uptake of both. T4: very similar uptake and distribution of both. T5: Ga-67 exceeded Tc-99m-MDP. The authors conclude that T5 is diagnostic of AOM, T3 and T4 raise the probability of AOM than before scanning, T1 and T2 decrease it.

Authors:: Tumeh, S S; Aliabadi, P; Weissman, B; McNeil, B J

Publication Date:: Wed May 01 00:00:00 EDT 1985

Research Org.:: Harvard Medical School, Boston, MA

OSTI Identifier:: 6759823

Report Number(s):: CONF-850611-
Journal ID: CODEN: JNMEA; TRN: 87-010732

Resource Type:: Conference

Journal Name:: J. Nucl. Med.; (United States)

Additional Journal Information:: Journal Volume: 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985

Country of Publication:: United States

Language:: English

Subject:: 62 RADIOLOGY AND NUCLEAR MEDICINE; BONE TISSUES; RADIONUCLIDE KINETICS; SCINTISCANNING; GALLIUM 67; TISSUE DISTRIBUTION; OSTEOMYELITIS; DIAGNOSIS; TECHNETIUM 99; UPTAKE; BONE FRACTURES; CORRELATIONS; DATA ANALYSIS; EVALUATION; PROSTHESES; RADIOPHARMACEUTICALS; SKELETAL DISEASES; ANIMAL TISSUES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CONNECTIVE TISSUE; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; DISTRIBUTION; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; GALLIUM ISOTOPES; HOURS LIVING RADIOISOTOPES; INJURIES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MEDICAL SUPPLIES; NUCLEI; ODD-EVEN NUCLEI; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM ISOTOPES; TISSUES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats


                    Tumeh, S S, Aliabadi, P, Weissman, B, and McNeil, B J. Abnormal Tc-99m-MDP/GA-67 scan patterns in association with active chronic osteomyelitis.  United States: N. p., 1985. 
        Web.

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                    Tumeh, S S, Aliabadi, P, Weissman, B, & McNeil, B J. Abnormal Tc-99m-MDP/GA-67 scan patterns in association with active chronic osteomyelitis.  United States.

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                    Tumeh, S S, Aliabadi, P, Weissman, B, and McNeil, B J. 1985.  
        "Abnormal Tc-99m-MDP/GA-67 scan patterns in association with active chronic osteomyelitis".  United States.

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@article{osti_6759823,

  title        = {Abnormal Tc-99m-MDP/GA-67 scan patterns in association with active chronic osteomyelitis},

  author       = {Tumeh, S S and Aliabadi, P and Weissman, B and McNeil, B J},

  abstractNote = {In this study the authors reviewed data from 136 patients (pts) in order to refine the interpretive criteria used to diagnose active osteomyelitis (AOM) in patients with previous bone disease (e.g., old osteomyelitis, fractures, orthopedic devices excluding prostheses). They evaluated bone (Tc-99mMDP) and gallium 67 studies and obtained followup in all pts. AOM was diagnosed by surgery or biopsy and culture in 49 pts and was excluded by the same criteria in 16 pts. An additional 71 pts had the diagnosis excluded by followup clinical criteria. Five patterns were found. T1: abnormal Tc-99m-MDP, normal Ga-67. T2: diffuse increased uptake of both radiopharmaceuticals with Tc-99m-MDP greater than Ga-67. T3: different geographic distribution, but similar intensities of uptake of both. T4: very similar uptake and distribution of both. T5: Ga-67 exceeded Tc-99m-MDP. The authors conclude that T5 is diagnostic of AOM, T3 and T4 raise the probability of AOM than before scanning, T1 and T2 decrease it.},

  doi          = {},

  url          = {https://www.osti.gov/biblio/6759823},
  journal      = {J. Nucl. Med.; (United States)},
number       = ,

  volume       = 26:5,

  place        = {United States},

  year         = {Wed May 01 00:00:00 EDT 1985},

  month        = {Wed May 01 00:00:00 EDT 1985}

}

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