Lung cancer detection using a miniature sodium iodide detector and cobalt-57 bleomycin
A small sodium iodide scintillation detector was designed for insertion through a fiberoptic bronchoscope to detect and localize sites of deposition of cobalt-57 bleomycin in lung cancer. The detector was used in 40 diagnostic studies of 34 patients; 21 of the patients had tumors. We compared the sensitivity, specificity, accuracy, and predictive value of the detector to those of plain chest x-ray films and bronchoscopy in detecting tumors. Sensitivity and specificity for the detector were 68 percent and 80 percent, respectively; for bronchoscopy, 72 percent and 100 percent; and for roentgenograms, 80 percent and 53 percent. Sensitivity for the detector and bronchoscopy combined was 92 percent. The detector succeeded in locating nonvisible submucosal and extraluminal tumors, and may contribute to early diagnosis and more accurate staging of lung cancer.
- Research Organization:
- Univ. of Arizona, Tucson
- OSTI ID:
- 6749507
- Journal Information:
- Chest; (United States), Vol. 85:1
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
BIOMEDICAL RADIOGRAPHY
COMPARATIVE EVALUATIONS
LUNGS
NEOPLASMS
SCINTILLATION COUNTING
DIAGNOSIS
BLEOMYCIN
COBALT 57
NAI DETECTORS
ANTI-INFECTIVE AGENTS
ANTIBIOTICS
ANTIMITOTIC DRUGS
ANTINEOPLASTIC DRUGS
BETA DECAY RADIOISOTOPES
BODY
COBALT ISOTOPES
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOTOPES
MEASURING INSTRUMENTS
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIATION DETECTORS
RADIOISOTOPES
RADIOLOGY
RESPIRATORY SYSTEM
SCINTILLATION COUNTERS
SOLID SCINTILLATION DETECTORS
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550602 - Medicine- External Radiation in Diagnostics- (1980-)