Enteric morbidity of postoperative pelvic external beam and brachytherapy for uterine cancer

Journal Article · Tue May 01 00:00:00 EDT 1990 · International Journal of Radiation Oncology, Biology and Physics; (USA)

DOI:https://doi.org/10.1016/0360-3016(90)90434-L· OSTI ID:6705510

Potish, R A; Dusenbery, K E ^[1]

---

1. Univ. of Minnesota Hospital and Clinic, Minneapolis (USA)

From 1970 through 1986, 219 women received postoperative pelvic external beam therapy and vaginal radium or cesium for uterine cancer. Prescribed external beam and total vaginal surface doses ranged from 38 to 51 Gy and from 70 to 119 Gy, respectively. Severe enteric morbidity developed in 7.8% of patients (15 small bowel, 1 sigmoid, 1 rectal). Complications occurred more frequently in patients with pelvic lymph node sampling at hysterectomy, abdominal surgery prior to hysterectomy, and low body weight. Logistic analysis demonstrated no significant effect of pelvic external beam dose, vaginal surface boost dose, or milligram hours. Five and 10-year overall survival rates were 85% and 74%, respectively. There were two proximal and one distal vaginal recurrences. Recommendations for avoiding complications are presented.

• OSTI ID: 6705510
• Journal Information: International Journal of Radiation Oncology, Biology and Physics; (USA), Vol. 18:5; ISSN 0360-3016
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
NEOPLASMS
RADIOTHERAPY
SIDE EFFECTS
UTERUS
CESIUM ISOTOPES
HEMORRHAGE
PATIENTS
PELVIS
RADIATION DOSES
RADIATION INJURIES
RADIUM ISOTOPES
RECOMMENDATIONS
SURVIVAL CURVES
ALKALI METAL ISOTOPES
ALKALINE EARTH ISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
DISEASES
DOSES
FEMALE GENITALS
INJURIES
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
ORGANS
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIOLOGY
SYMPTOMS
THERAPY
550603* - Medicine- External Radiation in Therapy- (1980-)
560151 - Radiation Effects on Animals- Man