Acute cytotoxicity of fossil-energy-related comparative research materials
Aqueous extracts of five fossil-energy-related comparative research materials have been examined under acute static conditions for toxic effects by use of the Tetrahymena assay system. Cells were exposed to various concentrations of extracts, and cytolysis and population growth impairment were monitored. In addition, chemical class fractionation and major organic elemental analysis were performed. Synthetic fossil fuel materials are more toxic than conventional petroleum crude oils and coal-derived materials are more toxic than crude shale oil. Synthetic fossil-fuel-related materials have a higher nitrogen and oxygen content and a greater aromaticity than do natural crude oils. Acute toxicity appears to be correlated with ether-soluble acid (phenolic) content, mono- and diaromatic hydrocarbon content, and ether-soluble base (primary aromatic amines and azaarenes) content.
- Research Organization:
- Oak Ridge National Lab., TN
- DOE Contract Number:
- W-7405-ENG-26
- OSTI ID:
- 6702728
- Journal Information:
- J. Environ. Sci. Health, Part A; (United States), Vol. A17:2
- Country of Publication:
- United States
- Language:
- English
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Acute cytotoxicity of fossil-energy-related comparative research materials
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Related Subjects
FOSSIL FUELS
BIOLOGICAL EFFECTS
QUALITATIVE CHEMICAL ANALYSIS
POLYCYCLIC AROMATIC HYDROCARBONS
TOXICITY
TETRAHYMENA
CELL KILLING
ANIMAL CELLS
BIOASSAY
GROWTH
INHIBITION
PHENOLS
SOLUBILITY
ANIMALS
AROMATICS
CHEMICAL ANALYSIS
CILIATA
ENERGY SOURCES
FUELS
HYDROCARBONS
HYDROXY COMPOUNDS
INVERTEBRATES
MICROORGANISMS
ORGANIC COMPOUNDS
PROTOZOA
560301* - Chemicals Metabolism & Toxicology- Cells- (-1987)