Chromosomal localization of mouse bullous pemphigoid antigens, BPAG1 and BPAG2: Identification of a new region of homology between mouse and human chromosomes
Journal Article
·
· Genomics; (United States)
- NCI-Frederick Cancer Research and Development Center, MD (United States)
- Jefferson Medical College, Philadelphia, PA (United States)
- Medical College of Wisconsin, Milwaukee (United States)
Two bullous pemphigoid antigens, BPAG1 and BPAG2, have been recently cloned and mapped to human chromosomes 6p12-p11 and 10q24.3, respectively. In this study, we localized the corresponding mouse genes by interspecific backcross analysis. Bpag-1 mapped to the proximal region of mouse chromosome 1, identifying a new region of homology between human chromosome 6 and mouse chromosome 1. Bpag-2 mapped to the distal end of mouse chromosome 19 in a region of homology to human chromosome 10q. These assignments confirm and extend the relationships between the human and the mouse chromosomes. 13 refs., 1 fig.
- OSTI ID:
- 6697312
- Journal Information:
- Genomics; (United States), Vol. 15:1; ISSN 0888-7543
- Country of Publication:
- United States
- Language:
- English
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