Validation study of gas chromatographic determination of pentachlorophenol in animal liver
A validation study was conducted of a gas chromatographic procedure for the determination of pentachlorophenol (PCP) in chicken, pork, and beef liver. Five analysts representing 5 laboratories analyzed randomly numbered blind duplicates at 3 fortified tissue concentrations and one incurred tissue on 2 consecutive days. The PCP concentrations ranged from approximately 40 to 400 parts per billion (ppb). All data were reported to 3 significant figures in ppb. The coefficients of variation for repeatability were between 2.8 and 8.5%, except for the beef liver, at a mean value of 80 ppb PCP, where the CV was 11.3%. The CVs for reproducibility were in the range of 9.7 - 16.5% with little significant difference by species. The CV asymptotically approached 10% as the PCP level increased.
- Research Organization:
- Huntingdon Analytical Services, Middleport, NY (USA)
- OSTI ID:
- 6676684
- Journal Information:
- J. Assoc. Off. Anal. Chem.; (United States), Vol. 71:5
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
CHLORINATED AROMATIC HYDROCARBONS
GAS CHROMATOGRAPHY
BIOLOGICAL ACCUMULATION
CATTLE
CHICKENS
INTERLABORATORY COMPARISONS
LIVER
SWINE
VALIDATION
ANIMALS
AROMATICS
BIRDS
BODY
CHROMATOGRAPHY
DIGESTIVE SYSTEM
DOMESTIC ANIMALS
FOWL
GLANDS
HALOGENATED AROMATIC HYDROCARBONS
MAMMALS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANS
RUMINANTS
SEPARATION PROCESSES
TESTING
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology