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Title: Changes in the electrical surface charge and transplantation properties of TA3 ascites tumor cells during short-term maintenance in an isotonic salt solution

Abstract

Several experimental procedures with tumors require in vitro maintenance of the cells under conditions that represent only an approximation to the physiological milieu. Examples of such procedures include the preparation of inocula for tumor transplantation and immunological studies on tumors in a cell culture system. Another example is the in vitro - in vivo cytotoxicity test in which the proliferative capacity of tumor cells is studied in vivo following incubation with a chemotherapeutic agent in vitro. As a means of characterizing several of the degenerative processes that can occur when tumor cells are maintained in vitro under relatively nonphysiological conditions, we have examined the influence of a 0.9% NaCl suspending medium on the surface charge and transplantation properties of TA3 ascites adenocarcinoma cells.

Authors:
; ;
Publication Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
OSTI Identifier:
6637558
Report Number(s):
LBL-11868
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Technical Report
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; ASCITES TUMOR CELLS; CELL PROLIFERATION; PATHOLOGICAL CHANGES; SURFACE PROPERTIES; CULTURE MEDIA; BIOLOGICAL EFFECTS; AQUEOUS SOLUTIONS; CELL CULTURES; CELL MEMBRANES; ELECTRIC CHARGES; EXPERIMENTAL DATA; IN VITRO; MICE; SALINITY; TEMPERATURE DEPENDENCE; TRANSPLANTS; ANIMAL CELLS; ANIMALS; CELL CONSTITUENTS; DATA; DISPERSIONS; INFORMATION; MAMMALS; MEMBRANES; MIXTURES; NUMERICAL DATA; RODENTS; SOLUTIONS; TUMOR CELLS; VERTEBRATES; 560301* - Chemicals Metabolism & Toxicology- Cells- (-1987); 550300 - Cytology

Citation Formats

Tenforde, T S, Richards, W R, and Kelly, L S. Changes in the electrical surface charge and transplantation properties of TA3 ascites tumor cells during short-term maintenance in an isotonic salt solution. United States: N. p., 1980. Web. doi:10.2172/6637558.
Tenforde, T S, Richards, W R, & Kelly, L S. Changes in the electrical surface charge and transplantation properties of TA3 ascites tumor cells during short-term maintenance in an isotonic salt solution. United States. https://doi.org/10.2172/6637558
Tenforde, T S, Richards, W R, and Kelly, L S. 1980. "Changes in the electrical surface charge and transplantation properties of TA3 ascites tumor cells during short-term maintenance in an isotonic salt solution". United States. https://doi.org/10.2172/6637558. https://www.osti.gov/servlets/purl/6637558.
@article{osti_6637558,
title = {Changes in the electrical surface charge and transplantation properties of TA3 ascites tumor cells during short-term maintenance in an isotonic salt solution},
author = {Tenforde, T S and Richards, W R and Kelly, L S},
abstractNote = {Several experimental procedures with tumors require in vitro maintenance of the cells under conditions that represent only an approximation to the physiological milieu. Examples of such procedures include the preparation of inocula for tumor transplantation and immunological studies on tumors in a cell culture system. Another example is the in vitro - in vivo cytotoxicity test in which the proliferative capacity of tumor cells is studied in vivo following incubation with a chemotherapeutic agent in vitro. As a means of characterizing several of the degenerative processes that can occur when tumor cells are maintained in vitro under relatively nonphysiological conditions, we have examined the influence of a 0.9% NaCl suspending medium on the surface charge and transplantation properties of TA3 ascites adenocarcinoma cells.},
doi = {10.2172/6637558},
url = {https://www.osti.gov/biblio/6637558}, journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Dec 01 00:00:00 EST 1980},
month = {Mon Dec 01 00:00:00 EST 1980}
}