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Title: Sutureless vascular end-to-end anastomosis. Final technical report Jan 82-Dec 83

Abstract

The objective of this project was to develop a means of rejoining severed vessels (end-to-end anastomosis) without using sutures. Two essential elements in the concept, an instrument to evert the vessel and a biocompatible, low-temperature (130 F/54 C), heat-shrinkage sleeve were developed. The sleeve, which contracts to accomplish the anastomosis, was developed by crosslinking (with ionizing gamma radiation) synthetic trans-1,4 polyisoprene. The crosslinked polymer was subjected to an acute toxicity screening program and proved to be highly biocompatible. The sutureless anastomosis technique was tested in-vitro on freshly excised pig carotid arteries however, there was insufficient funding available to provide for an evaluation of the technique in laboratory animals.

Authors:
Publication Date:
Research Org.:
Johns Hopkins Univ., Laurel, MD (USA). Applied Physics Lab.
OSTI Identifier:
6627802
Report Number(s):
AD-A-140484/7
Resource Type:
Technical Report
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BLOOD VESSELS; JOINING; POLYISOPRENE; CROSS-LINKING; SLEEVES; COMPATIBILITY; GAMMA RADIATION; MEDIUM TEMPERATURE; SWINE; ANIMALS; BODY; CARDIOVASCULAR SYSTEM; CHEMICAL REACTIONS; DOMESTIC ANIMALS; ELASTOMERS; ELECTROMAGNETIC RADIATION; FABRICATION; IONIZING RADIATIONS; MAMMALS; ORGANIC COMPOUNDS; ORGANIC POLYMERS; ORGANS; POLYMERIZATION; POLYMERS; RADIATIONS; VERTEBRATES; 550600* - Medicine

Citation Formats

Wozniak, J J. Sutureless vascular end-to-end anastomosis. Final technical report Jan 82-Dec 83. United States: N. p., 1984. Web.
Wozniak, J J. Sutureless vascular end-to-end anastomosis. Final technical report Jan 82-Dec 83. United States.
Wozniak, J J. 1984. "Sutureless vascular end-to-end anastomosis. Final technical report Jan 82-Dec 83". United States.
@article{osti_6627802,
title = {Sutureless vascular end-to-end anastomosis. Final technical report Jan 82-Dec 83},
author = {Wozniak, J J},
abstractNote = {The objective of this project was to develop a means of rejoining severed vessels (end-to-end anastomosis) without using sutures. Two essential elements in the concept, an instrument to evert the vessel and a biocompatible, low-temperature (130 F/54 C), heat-shrinkage sleeve were developed. The sleeve, which contracts to accomplish the anastomosis, was developed by crosslinking (with ionizing gamma radiation) synthetic trans-1,4 polyisoprene. The crosslinked polymer was subjected to an acute toxicity screening program and proved to be highly biocompatible. The sutureless anastomosis technique was tested in-vitro on freshly excised pig carotid arteries however, there was insufficient funding available to provide for an evaluation of the technique in laboratory animals.},
doi = {},
url = {https://www.osti.gov/biblio/6627802}, journal = {},
number = ,
volume = ,
place = {United States},
year = {Thu Mar 22 00:00:00 EST 1984},
month = {Thu Mar 22 00:00:00 EST 1984}
}

Technical Report:
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