Mutagenicity testing of high performance liquid chromatography fractions from wood stove emission samples using a modified Salmonella assay requiring smaller sample volumes

Journal Article · Sun Jan 01 00:00:00 EST 1984 · Environ. Mutagen.; (United States)

DOI:https://doi.org/10.1002/em.2860060111· OSTI ID:6609503

Alfheim, I; Becher, G; Hongslo, J K; Ramdahl, T

Organic extracts of emissions from wood combustion have been fractionated by high performance liquid chromatography (HPLC) into 25-28 fractions. Each fraction was tested for mutagenic activity in a modified Ames Salmonella/microsome bioassay requiring one-third of the test volumes needed for the ususal test. Direct mutagenic activity was noted predominantly in the most polar fractions, whereas indirect mutagenic activity was associated with the fractions containing polycyclic aromatic hydrocarbons (PAH) and with polar fractions probably consisting of aza-arenes and aromatic amines.

• Research Organization: Central Inst. for Industrial Research, Oslo, Norway
• OSTI ID: 6609503
• Journal Information: Environ. Mutagen.; (United States), Vol. 6:1
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINES
ECOLOGICAL CONCENTRATION
AZAARENES
GASEOUS WASTES
MUTAGEN SCREENING
POLYCYCLIC AROMATIC HYDROCARBONS
WOOD BURNING FURNACES
FRACTIONATION
LIQUID COLUMN CHROMATOGRAPHY
SALMONELLA
APPLIANCES
AROMATICS
BACTERIA
CHROMATOGRAPHY
FURNACES
HETEROCYCLIC COMPOUNDS
HYDROCARBONS
MICROORGANISMS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
SCREENING
SEPARATION PROCESSES
WASTES
WOOD BURNING APPLIANCES
500200* - Environment
Atmospheric- Chemicals Monitoring & Transport- (-1989)
560302 - Chemicals Metabolism & Toxicology- Microorganisms- (-1987)