CT patterns of splenic infarction: a clinical and experimental study

Conference · Fri Jun 01 00:00:00 EDT 1984 · Radiology; (United States)

OSTI ID:6603794

Balcar, I; Seltzer, S E; Davis, S; Geller, S

The computed tomographic (CT) appearance of splenic infarction has classically been described as peripheral, wedge-shaped, and low in density. Two investigations were designed to determine the appearance of splenic infarcts: (a) a clinical study of 12 patients and (b) a canine experimental model. In the clinical study, two previously undescribed patterns of splenic infarction were found. The classic peripheral, wedge-shaped defects were seen in four patients; multiple, heterogeneous lesions were seen in five; and massive hypodense lesions were noted in three. The experimental study of splenic infarction in dogs indicated that CT images can accurately depict the various phases of an infarct as it evolves through stages of congestion, hemorrhage, inflammation, organization, and fibrosis. In addition, a new contrast material - liposome-encapsulated diatrizoate - was used in one of the dogs and was found to produce greater and more sustained differences between normal and abnormal tissue than did conventional contrast material.

• Research Organization: Harvard Medical School, Boston, MA
• OSTI ID: 6603794
• Report Number(s): CONF-8311191-
• Journal Information: Radiology; (United States), Vol. 151:3; Conference: 69. annual meeting of the Radiological Society of North America, Chicago, IL, USA, 13 Nov 1983
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ISCHEMIA
DIAGNOSIS
SPLEEN
COMPUTERIZED TOMOGRAPHY
CONTRAST MEDIA
DOGS
FIBROSIS
HEMORRHAGE
INFLAMMATION
PATIENTS
ANIMALS
BODY
CARDIOVASCULAR DISEASES
DIAGNOSTIC TECHNIQUES
DISEASES
MAMMALS
ORGANS
PATHOLOGICAL CHANGES
SYMPTOMS
TOMOGRAPHY
VASCULAR DISEASES
VERTEBRATES
550602* - Medicine- External Radiation in Diagnostics- (1980-)