Quantitative gallium 67 lung scan to assess the inflammatory activity in the pneumoconioses

Journal Article · Thu Jan 01 00:00:00 EST 1987 · Semin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1016/S0001-2998(87)80008-9· OSTI ID:6592618

Bisson, G; Lamoureux, G; Begin, R

Gallium 67 lung scan has recently become increasingly used to evaluate the biological activity of alveolitis of interstitial lung diseases and to stage the disease process. In order to have a more precise and objective indicator of the inflammatory activity in the lung, we and others have developed computer-based quantitative techniques to process the /sup 67/Ga scan. In this report, we compare the results of three such computer-based methods of analysis of the scans of 38 normal humans and 60 patients suspected to have pneumoconiosis. Results of previous investigations on the mechanisms of /sup 67/Ga uptake in interstitial lung disease are reviewed. These data strengthen the view that quantitative /sup 67/Ga lung scan has become a standard technique to assess inflammatory activity in the interstitial lung diseases and that computer-based method of analysis of the scan provides an index of inflammatory activity of the lung disease that correlates with lung lavage and biopsy indices of inflammation in the lung tissue. 51 references.

• Research Organization: Universite de Sherbrooke, Quebec
• OSTI ID: 6592618
• Journal Information: Semin. Nucl. Med.; (United States), Vol. 1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
LUNGS
RADIOISOTOPE SCANNING
PNEUMOCONIOSES
DIAGNOSIS
COMPUTERIZED SIMULATION
GALLIUM 67
PATIENTS
BETA DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GALLIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
SIMULATION
550601* - Medicine- Unsealed Radionuclides in Diagnostics