Bilateral breast cancer: radiation therapy results and technical considerations. [/sup 60/Co]
A retrospective review was done of 34 women with bilateral breast carcinoma who received bilateral breast irradiation from 1964 to 1979. For the 31 curative patients, the 10-year actuarial survival rate after completion of irradiation to the second primary was 67%. Based upon the development of bilateral medial subcutaneous fibrosis/necrosis in 3/15 long-term survivors, various technical problems unique to bilateral breast irradiation were examined: In metachronous presentations, the dose to the contralateral subcutaneous medial tissue was determined as a function of the distance across the midline and the total dose that this point should receive if future contralateral IMC irradiation is required also. In synchronous presentations the doses to the spinal cord and anterior pericardium were determined for bilateral IMC irradiation as a function of modality, field width and energy. Suggestions for solving these technical problems are made, and the importance of permanent skin markings documenting portal placement to aid in possible future contralteral breast irradiation is stressed.
- Research Organization:
- Massachusetts General Hospital, Boston
- OSTI ID:
- 6570155
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 7:3
- Country of Publication:
- United States
- Language:
- English
Similar Records
Unilateral and Bilateral Breast Cancer in Women Surviving Pediatric Hodgkin's Disease
Contralateral breast cancer and other second malignancies in patients treated by breast-conserving therapy with radiation
Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
FIBROSIS
RADIOINDUCTION
MAMMARY GLANDS
DELAYED RADIATION EFFECTS
RADIATION DOSES
NECROSIS
RADIOTHERAPY
SIDE EFFECTS
SPINAL CORD
CARCINOMAS
COBALT 60
GAMMA RADIATION
SURVIVAL TIME
WOMEN
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CENTRAL NERVOUS SYSTEM
COBALT ISOTOPES
DISEASES
DOSES
ELECTROMAGNETIC RADIATION
FEMALES
GLANDS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MAN
MEDICINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NERVOUS SYSTEM
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATHOLOGICAL CHANGES
PRIMATES
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RADIOLOGY
THERAPY
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560151* - Radiation Effects on Animals- Man
550603 - Medicine- External Radiation in Therapy- (1980-)