Fecal blood loss in patients with colonic polyps: a comparison of measurements with 51chromium-labeled erythrocytes and with the Haemoccult test

Journal Article · Mon Nov 01 00:00:00 EST 1982 · Gastroenterology; (United States)

OSTI ID:6569737

Herzog, P; Holtermueller, K H; Preiss, J; Fischer, J; Ewe, K; Schreiber, H J; Berres, M

The quantitative determinations of fecal daily blood loss after intravenous administration of /sup 51/Cr-labeled erythrocytes in 44 patients with colonic polyps and in 11 controls were compared with the results of the daily performed Haemoccult test without dietary restrictions. A total of 642 stool specimens was analyzed for /sup 51/Cr loss and the Haemoccult test. The mean fecal daily blood loss in the 34 patients with adenomatous polyps of the descending colon and rectosigmoid was 1.36 +/- 0.14 ml/day (mean +/- SEM), in the 10 patients with polyps of the ascending and transverse colon it was 1.28 +/- 0.31 ml/day, and in the 11 controls 0.62 +/- 0.07 ml/day. There was no positive Haemoccult test in the controls. In fecal specimens from patients with polyps in the descending colon and rectosigmoid containing 2.0-3.99 ml blood/day, the Haemoccult-test was positive in 86%. Fecal specimens from patients with polyps in the ascending colon and transverse colon containing equal blood loss yielded a positive Haemoccult test result in 26%. Thus, the positivity of the Haemoccult test is determined by the fecal daily blood loss and the anatomic location of colonic bleeding sites.

• Research Organization: Medizinische Klinik und Poliklinik, Universitaet Mainz, Federal Republic of Germany
• OSTI ID: 6569737
• Journal Information: Gastroenterology; (United States), Vol. 83:5
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
DIGESTIVE SYSTEM DISEASES
DIAGNOSTIC TECHNIQUES
CHROMIUM 51
HEMORRHAGE
LARGE INTESTINE
PATIENTS
TRACER TECHNIQUES
BETA DECAY RADIOISOTOPES
BODY
CHROMIUM ISOTOPES
DIGESTIVE SYSTEM
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
GASTROINTESTINAL TRACT
INTERMEDIATE MASS NUCLEI
INTESTINES
ISOTOPE APPLICATIONS
ISOTOPES
NUCLEI
ORGANS
PATHOLOGICAL CHANGES
RADIOISOTOPES
SYMPTOMS
550601* - Medicine- Unsealed Radionuclides in Diagnostics