Effect of cyclic aromatics on sodium active transport in frog skin
- Oklahoma State Univ., Stillwater (United States)
A modified glass Ussing-chamber was used to mount the skin. The electrical potential difference (PD) was measured by two 3% agar-frog Ringer's bridges. Current (i.e. short-circuit current, or ISC) was passed by Ag-AgCl electrodes placed so that current density was uniform across the skin. Ringer's solution, bathing each side of the frog skin, was stirred and aerated by gas-lift pumps. The effect of toxicants on the ISC was determined by using the 15 min prior to toxicant administration as a control period, then calculating the change in ISC during the toxicant period as a percent of the control ISC. Phenol and benzene are components of crude oil and crude oil waste. These hydrocarbons and phenanthrene were tested for their effect on frog skin. The results show that the effect of organics on sodium active transport of an epithelium is to alter the active transport of sodium ions. 5 refs., 3 figs., 1 tab.
- OSTI ID:
- 6568653
- Journal Information:
- Bulletin of Environmental Contamination and Toxicology; (United States), Vol. 50:1; ISSN 0007-4861
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
02 PETROLEUM
BENZENE
BIOLOGICAL EFFECTS
PETROLEUM
PHENANTHRENE
PHENOL
FROGS
MEMBRANE TRANSPORT
NAPHTHALENE
SKIN
SODIUM IONS
AMPHIBIANS
ANIMALS
AQUATIC ORGANISMS
AROMATICS
BODY
CHARGED PARTICLES
CONDENSED AROMATICS
ENERGY SOURCES
FOSSIL FUELS
FUELS
HYDROCARBONS
HYDROXY COMPOUNDS
IONS
ORGANIC COMPOUNDS
ORGANS
PHENOLS
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology
020600 - Petroleum- Health & Safety