Calcium regulation in frog peripheral nerve by the blood-nerve barrier
The objectives of this research were: (a) to investigate the characteristics of calcium transport across the perineurium and the endoneurial capillaries, and (b) to gain a better understanding of the extent of calcium homeostasis in the endoneurial space. To study the nature of calcium transport across the perineurium, the flux of radiotracer /sup 45/Ca was measured through the perineurial cylinder, isolated from the frog sciatic nerve, and through the perineurium into the nerve in situ. To study the nature of calcium transport across the endoneurial capillaries, the permeability-surface area product (PA) of /sup 45/Ca was determined as a function of the calcium concentration in the blood. To study calcium homeostasis, the calcium content of the frog sciatic nerve was determined as a function of chronic changes in plasma (Ca).
- Research Organization:
- Maryland Univ., College Park (USA)
- OSTI ID:
- 6550328
- Resource Relation:
- Other Information: Thesis (Ph. D)
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
CALCIUM
MEMBRANE TRANSPORT
CAPILLARIES
PERMEABILITY
NERVES
BIOLOGICAL FUNCTIONS
BLOOD
CALCIUM 45
FROGS
HOMEOSTASIS
TRACER TECHNIQUES
ALKALINE EARTH ISOTOPES
ALKALINE EARTH METALS
AMPHIBIANS
ANIMALS
AQUATIC ORGANISMS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD VESSELS
BODY
BODY FLUIDS
CALCIUM ISOTOPES
CARDIOVASCULAR SYSTEM
DAYS LIVING RADIOISOTOPES
ELEMENTS
EVEN-ODD NUCLEI
FUNCTIONS
INTERMEDIATE MASS NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
MATERIALS
METALS
NERVOUS SYSTEM
NUCLEI
ORGANS
RADIOISOTOPES
VERTEBRATES
550201* - Biochemistry- Tracer Techniques