Effect of ingested benzo(a)pyrene and cadmium on tissue accumulation, hydroxylase activity, and intestinal morphology of the black sea bass, Centropristis striata

Journal Article · Sun Feb 01 00:00:00 EST 1987 · Environ. Res.; (United States)

DOI:https://doi.org/10.1016/S0013-9351(87)80020-8· OSTI ID:6515660

Fair, P H; Fortner, A R

Black sea bass, Centropristis striata, were fed shrimp containing (/sup 14/C)benzo(a)pyrene (200 ppb) in the presence and absence of cadmium (10 ppm) for 10 days. Concentrations of cadmium in muscle tissue were significantly higher when both cadmium and benzo(a)pyrene were ingested simultaneously by the fish. Results indicate that selected tissue concentrations of total benzo(a)pyrene compounds (parent and metabolites) were not affected by the presence of cadmium. The bile contained the majority of benzo(a)pyrene found for all treatments. Ingestion of both contaminants had no effect on hepatic benzo(a)pyrene hydroxylase activity. Histological evidence from the feeding study demonstrated the presence of subcellular inclusions in the intestinal columnar cells and the combined effects of both contaminants appeared greater than either alone.

• Research Organization: National Marine Fisheries Service, Charleston, SC
• OSTI ID: 6515660
• Journal Information: Environ. Res.; (United States), Vol. 42:1
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BENZOPYRENE
TISSUE DISTRIBUTION
TOXICITY
CADMIUM
HYDROXYLASES
ENZYME ACTIVITY
INTESTINES
MORPHOLOGICAL CHANGES
BIOLOGICAL ACCUMULATION
CARBON 14 COMPOUNDS
SYNERGISM
TRACER TECHNIQUES
AROMATICS
BODY
CONDENSED AROMATICS
DIGESTIVE SYSTEM
DISTRIBUTION
ELEMENTS
ENZYMES
GASTROINTESTINAL TRACT
HYDROCARBONS
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
METALS
ORGANIC COMPOUNDS
ORGANS
OXIDOREDUCTASES
560300* - Chemicals Metabolism & Toxicology