Effect of suture material on platelet deposition onto prosthetic material
Previous studies have demonstrated the importance of employing prosthetic material with minimal thrombogenicity. However, the role of different suture materials in early thrombotic events on prosthetic materials has not been examined. Experiments were designed to analyze the effects of suture on platelet graft interaction using an in vivo baboon hemocompatability screen. Indium labeled, autologous platelet deposition was determined on expanded polytetrafluoroethylene (ePTFE) containing suture lines of polypropylene (Prolene), polybutester (Novafil), and ePTFE (Gore-Tex). A significant increase in platelet deposition was noted not only at the suture line, but proximal and distal to it as well. The results were different for each of the sutures employed and suggest that the suture line may influence early platelet deposition in the perianastomotic region, not only at the suture line, but proximally and distally as well.
- Research Organization:
- Tufts Univ. School of Medicine, Boston, MA (USA)
- OSTI ID:
- 6515074
- Journal Information:
- ASAIO Trans.; (United States), Vol. 34:3
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
BLOOD PLATELETS
ADHESION
PROSTHESES
MATERIALS TESTING
BABOONS
CHEMICAL PROPERTIES
INDIUM 111
PLASTICS
POLYESTERS
POLYTETRAFLUOROETHYLENE
THROMBOSIS
TRACER TECHNIQUES
ANIMALS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARDIOVASCULAR DISEASES
DAYS LIVING RADIOISOTOPES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ESTERS
FLUORINATED ALIPHATIC HYDROCARBONS
HALOGENATED ALIPHATIC HYDROCARBONS
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
MATERIALS
MEDICAL SUPPLIES
MINUTES LIVING RADIOISOTOPES
MONKEYS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC FLUORINE COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC POLYMERS
PETROCHEMICALS
PETROLEUM PRODUCTS
POLYETHYLENES
POLYMERS
POLYOLEFINS
PRIMATES
RADIOISOTOPES
SYNTHETIC MATERIALS
TESTING
VASCULAR DISEASES
VERTEBRATES
550901* - Pathology- Tracer Techniques