External radiation therapy of stage I cancer of the endometrium: a need for reappraisal of this adjunctive modality
Abstract
One hundred and eighty-five patients with Stage I cancer of the endometrium were irradiated preoperatively. All were irradiated to the whole pelvis by external beam only using supermegavoltage apparati. The total mid-pelvis dose ranged from 4500 cGy/5 weeks to 5500 cGy/6 1/2 weeks. Surgery followed usually in 6 weeks. Complications were minimal. Disease-free survival at Stage IA was 92.4% 5-year, 87.7% 10-year; Stage IB was 83.5% 5-year, 74.6% 10-year. Prognosis was related to stage, grade, depth of myometrial penetration, the presence of residual tumor at hysterectomy. External beam preoperative irradiation is recommended for all Stage I patients; Stage IB with higher grade pathology should have intracavitary irradiation supplemental to the external irradiation.
- Authors:
- Publication Date:
- Research Org.:
- St. Mary's Hospital, San Francisco, CA (USA)
- OSTI Identifier:
- 6486465
- Resource Type:
- Journal Article
- Journal Name:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States)
- Additional Journal Information:
- Journal Volume: 15:6
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 62 RADIOLOGY AND NUCLEAR MEDICINE; NEOPLASMS; RADIOTHERAPY; UTERUS; PATIENTS; PELVIS; RADIATION DOSES; SURGERY; SURVIVAL CURVES; BODY; BODY AREAS; DISEASES; DOSES; FEMALE GENITALS; MEDICINE; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; THERAPY; 550603* - Medicine- External Radiation in Therapy- (1980-); 550600 - Medicine
Citation Formats
Vaeth, J M, Fontanesi, J, Tralins, A H, and Chauser, B M. External radiation therapy of stage I cancer of the endometrium: a need for reappraisal of this adjunctive modality. United States: N. p., 1988.
Web. doi:10.1016/0360-3016(88)90223-4.
Vaeth, J M, Fontanesi, J, Tralins, A H, & Chauser, B M. External radiation therapy of stage I cancer of the endometrium: a need for reappraisal of this adjunctive modality. United States. https://doi.org/10.1016/0360-3016(88)90223-4
Vaeth, J M, Fontanesi, J, Tralins, A H, and Chauser, B M. 1988.
"External radiation therapy of stage I cancer of the endometrium: a need for reappraisal of this adjunctive modality". United States. https://doi.org/10.1016/0360-3016(88)90223-4.
@article{osti_6486465,
title = {External radiation therapy of stage I cancer of the endometrium: a need for reappraisal of this adjunctive modality},
author = {Vaeth, J M and Fontanesi, J and Tralins, A H and Chauser, B M},
abstractNote = {One hundred and eighty-five patients with Stage I cancer of the endometrium were irradiated preoperatively. All were irradiated to the whole pelvis by external beam only using supermegavoltage apparati. The total mid-pelvis dose ranged from 4500 cGy/5 weeks to 5500 cGy/6 1/2 weeks. Surgery followed usually in 6 weeks. Complications were minimal. Disease-free survival at Stage IA was 92.4% 5-year, 87.7% 10-year; Stage IB was 83.5% 5-year, 74.6% 10-year. Prognosis was related to stage, grade, depth of myometrial penetration, the presence of residual tumor at hysterectomy. External beam preoperative irradiation is recommended for all Stage I patients; Stage IB with higher grade pathology should have intracavitary irradiation supplemental to the external irradiation.},
doi = {10.1016/0360-3016(88)90223-4},
url = {https://www.osti.gov/biblio/6486465},
journal = {Int. J. Radiat. Oncol., Biol. Phys.; (United States)},
number = ,
volume = 15:6,
place = {United States},
year = {Thu Dec 01 00:00:00 EST 1988},
month = {Thu Dec 01 00:00:00 EST 1988}
}