Modeling of enzyme immobilization in porous membranes
Journal Article
·
· Biotechnol. Bioeng.; (United States)
This article deals with the mathematical modeling of the process of enzyme immobilization in porous membranes. During the initial period, an analytical solution is available to extract the rate constant for immobilization. Beyond this period, the model equations are solved numerically to yield the transient response of the enzyme concentration in the immobilizing solution and also the evolution of the enzyme loading profile inside the membrane. It is found that the immobilization practically ceases even though the attachment sites are still available within the membrane.
- Research Organization:
- Univ. of Queensland, St. Lucia, Australia
- OSTI ID:
- 6482334
- Journal Information:
- Biotechnol. Bioeng.; (United States), Vol. 27:8
- Country of Publication:
- United States
- Language:
- English
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