Mimic of superoxide dismutase activity protects Chlorella sorokiniana against the toxicity of sulfite
Journal Article
·
· Free Radic. Biol. Med.; (United States)
The spin-trapping agent 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) has been used to demonstrate the light-dependent production of O/sub 2/- by Chlorella sorokiniana. In the presence of SO/sub 3/= a light-dependent production of the sulfur trioxy anion radical (SO/sub 3/-.) could also be seen. A complex prepared by reacting desferrioxamine with MnO/sub 2/, which catalyzes the dismutation of O/sub 2/-, protected the alga against the toxicity of sulfite. The data suggest that SO/sub 2/ toxicity is at least partially due to the effects of sulfoxy-free radicals generated by the oxidation of SO3= by O/sub 2/-.
- Research Organization:
- Hebrew Univ. of Jerusalem, Rehovot (Israel)
- OSTI ID:
- 6459193
- Journal Information:
- Free Radic. Biol. Med.; (United States), Vol. 6:1
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
SULFITES
TOXICITY
SULFUR DIOXIDE
SUPEROXIDE DISMUTASE
ENZYME ACTIVITY
SUPEROXIDE RADICALS
BIOSYNTHESIS
CATALYSTS
CHLORELLA
DEFEROXAMINE
ELECTRON SPIN RESONANCE
MANGANESE
ALGAE
AMINES
CHALCOGENIDES
CHELATING AGENTS
CHLOROPHYCOTA
ELEMENTS
ENZYMES
MAGNETIC RESONANCE
METALS
MICROORGANISMS
ORGANIC COMPOUNDS
OXIDES
OXIDOREDUCTASES
OXYGEN COMPOUNDS
PLANTS
RADICALS
RESONANCE
SULFUR COMPOUNDS
SULFUR OXIDES
SYNTHESIS
TRANSITION ELEMENTS
UNICELLULAR ALGAE
560300* - Chemicals Metabolism & Toxicology
SULFITES
TOXICITY
SULFUR DIOXIDE
SUPEROXIDE DISMUTASE
ENZYME ACTIVITY
SUPEROXIDE RADICALS
BIOSYNTHESIS
CATALYSTS
CHLORELLA
DEFEROXAMINE
ELECTRON SPIN RESONANCE
MANGANESE
ALGAE
AMINES
CHALCOGENIDES
CHELATING AGENTS
CHLOROPHYCOTA
ELEMENTS
ENZYMES
MAGNETIC RESONANCE
METALS
MICROORGANISMS
ORGANIC COMPOUNDS
OXIDES
OXIDOREDUCTASES
OXYGEN COMPOUNDS
PLANTS
RADICALS
RESONANCE
SULFUR COMPOUNDS
SULFUR OXIDES
SYNTHESIS
TRANSITION ELEMENTS
UNICELLULAR ALGAE
560300* - Chemicals Metabolism & Toxicology