Zinc and magnesium concentrations in plasma and red blood cells in patients on digitalis medication

Conference · Mon Jun 01 00:00:00 EDT 1981 · Trace Subst. Environ. Health; (United States)

OSTI ID:6428149

Zumkley, H; Bertram, H P; Vetter, H; Zidek, W; Wessels, F

Determinations of zinc, sodium, potassium and magnesium in plasma and red blood cells (RBC) were performed in 31 controls and 63 patients treated with digitalis. In digitalized patients Na and Zn concentrations in RBC were significantly increased, whereas the intraerythrocyte Mg concentration was only slightly elevated. Plasma concentrations of all investigated electrolytes as well as of Zn remained within the normal range. There was a close relationship between the increase of Na and Zn content in RBC indicating alterations in transmembrane transport mechanisms induced by digitalis therapy.

• Research Organization: Medizinische Universitaets Poliklinik, Muenster, Germany
• OSTI ID: 6428149
• Report Number(s): CONF-8106251-
• Journal Information: Trace Subst. Environ. Health; (United States), Vol. 15; Conference: 15. annual conference on trace substances in environmental health, Columbia, MO, USA, 1 Jun 1981
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
DIGITALIS GLYCOSIDES
BIOLOGICAL EFFECTS
MAGNESIUM
METABOLISM
ZINC
BLOOD PLASMA
ERYTHROCYTES
MEMBRANE TRANSPORT
PATIENTS
SODIUM
ALKALI METALS
ALKALINE EARTH METALS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARBOHYDRATES
CARDIAC GLYCOSIDES
CARDIOTONICS
CARDIOVASCULAR AGENTS
DRUGS
ELEMENTS
GLYCOSIDES
MATERIALS
METALS
ORGANIC COMPOUNDS
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
550500 - Metabolism
550200 - Biochemistry