Physicochemical processes and the formulation of dosimetry models. [Transport and absorption of ozone and nitrogen dioxide in the respiratory tract]

Journal Article · Sun Jan 01 00:00:00 EST 1984 · J. Toxicol. Environ. Health; (United States)

DOI:https://doi.org/10.1080/15287398409530498· OSTI ID:6410263

Overton, Jr, J H

The major physical and chemical processes involved in the transport and absorption of O/sub 3/ or NO/sub 2/ in the lower respiratory tract are discussed. This included the development of respiratory tract models, flow patterns, and transport in tube networks, the mucous, surfactant, and tissue layers, and chemical reactions and transport of O/sub 3/ or NO/sub 2/ within these layers. Descriptions of the individual processes are simplified and integrated to illustrate the formulation of dosimetry models. Data from a dosimetry model, formulated from the concepts discussed, are used to illustrate the types of information obtained by modeling. 31 references.

• Research Organization: Northrop Services, Inc., Research Triangle Park, NC
• OSTI ID: 6410263
• Journal Information: J. Toxicol. Environ. Health; (United States), Vol. 13:2-3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
54 ENVIRONMENTAL SCIENCES
NITROGEN DIOXIDE
TISSUE DISTRIBUTION
UPTAKE
OZONE
RESPIRATORY SYSTEM
MATHEMATICAL MODELS
PHYSIOLOGY
BIOCHEMICAL REACTION KINETICS
DOSE-RESPONSE RELATIONSHIPS
LUNGS
BODY
CHALCOGENIDES
DISTRIBUTION
KINETICS
NITROGEN COMPOUNDS
NITROGEN OXIDES
ORGANS
OXIDES
OXYGEN COMPOUNDS
REACTION KINETICS
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