skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Breast-milk radioactivity after a Tc-99m DTPA aerosol/Tc-99m MAA lung study

Abstract

Measurements were made of the concentration of Tc-99m activity in samples of breast milk following an administration of Tc-99m DTPA aerosol for a lung ventilation image and one of Tc-99m MAA for lung perfusion. The activity was 222 nCi/ml of milk (8.2 kBq/ml) at 2 hr after the MAA injection, and it was found to be excreted exponentially with an effective half-life of 4.6 hr. There was a small incorporation of Tc-99m into breast-milk protein. The authors conclude that the combined use of these two Tc-99m agents did not indicate the interruption of breast feeding beyond 24 hr after administration of the MAA, and that for an aerosol ventiliation study alone, breast feeding need not be interrupted for more than 4 hr after the test.

Authors:
; ; ;
Publication Date:
Research Org.:
Kent and Canterbury Hospital, England
OSTI Identifier:
6385409
Resource Type:
Journal Article
Journal Name:
J. Nucl. Med.; (United States)
Additional Journal Information:
Journal Volume: 25:10
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; 59 BASIC BIOLOGICAL SCIENCES; INFANTS; RADIATION DOSES; LUNGS; SCINTISCANNING; MILK; RETENTION FUNCTIONS; TECHNETIUM 99; UPTAKE; AEROSOLS; ALBUMINS; DTPA; EMBOLI; ISOMERIC NUCLEI; LACTATION; AGE GROUPS; AMINO ACIDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BODY; BODY FLUIDS; CARBOXYLIC ACIDS; CHELATING AGENTS; CHILDREN; COLLOIDS; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DISPERSIONS; DOSES; DRUGS; FOOD; FUNCTIONS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; PROTEINS; RADIOISOTOPE SCANNING; RADIOISOTOPES; RADIOPROTECTIVE SUBSTANCES; RESPIRATORY SYSTEM; SOLS; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES; 560161* - Radionuclide Effects, Kinetics, & Toxicology- Man; 550601 - Medicine- Unsealed Radionuclides in Diagnostics; 550501 - Metabolism- Tracer Techniques

Citation Formats

Mountford, P J, Hall, F M, Wells, C P, and Coakley, A J. Breast-milk radioactivity after a Tc-99m DTPA aerosol/Tc-99m MAA lung study. United States: N. p., 1984. Web.
Mountford, P J, Hall, F M, Wells, C P, & Coakley, A J. Breast-milk radioactivity after a Tc-99m DTPA aerosol/Tc-99m MAA lung study. United States.
Mountford, P J, Hall, F M, Wells, C P, and Coakley, A J. 1984. "Breast-milk radioactivity after a Tc-99m DTPA aerosol/Tc-99m MAA lung study". United States.
@article{osti_6385409,
title = {Breast-milk radioactivity after a Tc-99m DTPA aerosol/Tc-99m MAA lung study},
author = {Mountford, P J and Hall, F M and Wells, C P and Coakley, A J},
abstractNote = {Measurements were made of the concentration of Tc-99m activity in samples of breast milk following an administration of Tc-99m DTPA aerosol for a lung ventilation image and one of Tc-99m MAA for lung perfusion. The activity was 222 nCi/ml of milk (8.2 kBq/ml) at 2 hr after the MAA injection, and it was found to be excreted exponentially with an effective half-life of 4.6 hr. There was a small incorporation of Tc-99m into breast-milk protein. The authors conclude that the combined use of these two Tc-99m agents did not indicate the interruption of breast feeding beyond 24 hr after administration of the MAA, and that for an aerosol ventiliation study alone, breast feeding need not be interrupted for more than 4 hr after the test.},
doi = {},
url = {https://www.osti.gov/biblio/6385409}, journal = {J. Nucl. Med.; (United States)},
number = ,
volume = 25:10,
place = {United States},
year = {Mon Oct 01 00:00:00 EDT 1984},
month = {Mon Oct 01 00:00:00 EDT 1984}
}