Osteomyelitis complicating fracture: pitfalls of /sup 111/In leukocyte scintigraphy
/sup 111/In-labeled leukocyte imaging has shown greater accuracy and specificity than alternative noninvasive methods in the detection of uncomplicated osteomyelitis. Forty patients with suspected osteomyelitis complicating fractures (with and without surgical intervention) were evaluated with /sup 111/In-labeled leukocytes. All five patients with intense focal uptake, but only one of 13 with no uptake, had active osteomyelitis. However, mild to moderate /sup 111/In leukocyte uptake, observed in 22 cases, indicated the presence of osteomyelitis in only four of these; the other false-positive results were observed in noninfected callus formation, heterotopic bone formation, myositis ossificans, and sickle-cell disease. These results suggest that /sup 111/In-labeled leukocyte imaging is useful for the evaluation of suspected osteomyelitis complicating fracture but must be used in conjunction with clinical and radiographic correlation to avoid false-positive results.
- Research Organization:
- Univ. of Texas Medical School, Houston
- OSTI ID:
- 6354724
- Journal Information:
- AJR, Am. J. Roentgenol.; (United States), Vol. 5
- Country of Publication:
- United States
- Language:
- English
Similar Records
Indium-111 leukocyte scintigraphic detection of subclinical osteomyelitis complicating delayed and nonunion long bone fractures: a prospective study
Diagnosis of osteomyelitis of the foot in diabetic patients: Value of 111In-leukocyte scintigraphy
Related Subjects
LEUKOCYTES
SCINTISCANNING
OSTEOMYELITIS
DIAGNOSIS
BONE FRACTURES
INDIUM 111
PATIENTS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
INDIUM ISOTOPES
INJURIES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATERIALS
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-EVEN NUCLEI
RADIOISOTOPE SCANNING
RADIOISOTOPES
SKELETAL DISEASES
550601* - Medicine- Unsealed Radionuclides in Diagnostics