Glass microspheres
This patent describes a glass microsphere having a diameter of about 54 micrometers or less and adapted for radiation therapy of a mammal. The glass consists of essentially an yttrium oxide-aluminosilicate glass composition lying substantially within a quadrilateral region of the ternary composition diagram of the yttria-alumina-silica system, the quadrilateral region being defined by its four corners having the following combination of weight proportions of the components: 20% silica, 10% alumina, 70% yttria; 70% silica, 10% alumina, 20% yttria; 70% silica, 20% alumina, 10% yttria; and 20% silica, 45% alumina, 35% yttria, the glass having a chemical durability such that subsequent to irradiation and administration of the microsphere to the mammal, the mircosphere will not release a significant amount of yttrium-90 into the mammal's system.
- Assignee:
- Curators of the Univ. of Missouri, Columbia, MO
- Patent Number(s):
- US 4789501
- Application Number:
- TRN: 89-007474
- OSTI ID:
- 6348522
- Resource Relation:
- Patent File Date: Filed date 19 Nov 1984
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
36 MATERIALS SCIENCE
GLASS
THERAPEUTIC USES
MAMMALS
RADIOTHERAPY
ALUMINIUM OXIDES
ALUMINIUM SILICATES
CHEMICAL COMPOSITION
CHEMICAL PROPERTIES
DIMENSIONS
IRRADIATION
QUANTITY RATIO
SILICA
SPHERES
YTTRIUM 90
YTTRIUM OXIDES
ALUMINIUM COMPOUNDS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CHALCOGENIDES
DAYS LIVING RADIOISOTOPES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MINERALS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
OXIDE MINERALS
OXIDES
OXYGEN COMPOUNDS
RADIOISOTOPES
RADIOLOGY
SILICATES
SILICON COMPOUNDS
SILICON OXIDES
THERAPY
TRANSITION ELEMENT COMPOUNDS
USES
VERTEBRATES
YTTRIUM COMPOUNDS
YTTRIUM ISOTOPES
550603* - Medicine- External Radiation in Therapy- (1980-)
360206 - Ceramics
Cermets
& Refractories- Radiation Effects